AJDRAJNR - American Journal of Neuroradiology

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Engelbrecht, V.
Right arrow Articles by Wendel, U.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Engelbrecht, V.
Right arrow Articles by Wendel, U.

American Journal of Neuroradiology, Vol 18, Issue 3 536-539, Copyright © 1997 by American Society of Neuroradiology

ARTICLES

MR and proton MR spectroscopy of the brain in hyperhomocysteinemia caused by methylenetetrahydrofolate reductase deficiency

V Engelbrecht, M Rassek, J Huismann and U Wendel
Institute of Diagnostic Radiology, Heinrich-Heine University Dusseldorf, Germany.

MR imaging showed severe atrophy and large areas without myelination in the brain of a girl with methylenetetrahydrofolate reductase deficiency. Proton MR spectroscopy revealed mild signal reduction of N- acetylaspartate. After treatment with betaine, a second MR imaging study revealed a decrease in the size of the hypomyelinated zones that was paralleled by improved clinical status and laboratory findings.


This article has been cited by other articles:


Home page
 J Child NeurolHome page
D. L. Smith and O. A. Bodamer
Practical Management of Combined Methylmalonicaciduria and Homocystinuria
J Child Neurol, May 1, 2002; 17(5): 353 - 356.
[Abstract] [PDF]


Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X