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American Journal of Neuroradiology, Vol 18, Issue 5 951-958, Copyright © 1997 by American Society of Neuroradiology


ARTICLES

Premature fat deposition in the salivary glands associated with Sjogren syndrome: MR and CT evidence

M Izumi, K Eguchi, H Nakamura, S Nagataki and T Nakamura
Department of Radiology, Nagasaki University School of Dentistry, Sakamoto, Japan.

PURPOSE: To investigate abnormal fat deposition in the major salivary glands associated with Sjogren syndrome. METHODS: We analyzed the fat deposition in the parotid and submandibular glands of 33 patients with Sjogren syndrome by using short-inversion-time inversion recovery (STIR) and fat-saturation MR sequences and CT values. RESULTS: All three in vivo techniques substantially confirmed premature deposition of fat in the major salivary glands in association with Sjogren syndrome. Furthermore, this change was characteristic of Sjogren syndrome, and the severity of fat deposition correlated well with the impaired rates of salivary flow in these patients. CONCLUSION: Monitoring of fat deposition might be useful for diagnosing Sjogren syndrome and assessing its progress in patients whose clinical and serologic findings are suggestive of the disease.


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