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American Journal of Neuroradiology, Vol 18, Issue 9 1749-1752, Copyright © 1997 by American Society of Neuroradiology


ARTICLES

Persistent high MR signal of the posterior pituitary gland in central diabetes insipidus

M Maghnie, E Genovese, S Bernasconi, S Binda and M Arico
Department of Pediatrics, University, IRCCS Policlinico S. Matteo, Pavia, Italy.

We describe three cases of central diabetes insipidus, each with a different pathogenesis, in which unexpected hyperintensity of the posterior pituitary gland was seen on T1-weighted MR images obtained at the time of presentation. In the first case (idiopathic), the posterior pituitary signal persisted more than 10 years; in the second case (Langerhans cell histiocytosis), the signal disappeared within 3 months, despite early specific chemotherapy with etoposide; and in the third case (transient), the posterior signal disappeared within 1 year, but it was documented at the time of spontaneous reversal of polyuria and polydipsia.


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