American Journal of Neuroradiology, Vol 19, Issue 10 1905-1907, Copyright © 1998 by American Society of Neuroradiology
ARTICLES |
MR imaging technique for the diagnosis of pituitary iron overload in patients with transfusion-dependent beta-thalassemia major
G Sparacia, A Banco, M Midiri and A Iaia
Institute of Radiology P. Cignolini, University of Palermo, Italy.
To identify the optimal MR imaging technique for diagnosing pituitary iron overload, we compared spin-echo and gradient-echo MR imaging with measurements of pituitary T2 relaxation times in 30 patients with secondary hemochromatosis due to transfusion-dependent beta-thalassemia major and in 10 healthy volunteers. We found that the optimal MR imaging technique to evaluate pituitary iron overload is the gradient- echo T2*-weighted technique, as it best demonstrated signal reduction in the anterior lobe of the pituitary gland.
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