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American Journal of Neuroradiology, Vol 19, Issue 3 454-455, Copyright © 1998 by American Society of Neuroradiology


ARTICLES

The role of 99m-Tc HMPAO SPECT in the diagnosis of Creutzfeldt-Jacob disease

DA Miller, RA Vitti and MM Maslack
Department of Radiology, Pennsylvania Hospital, Philadelphia, USA.

A patient with acute dementia underwent imaging of the brain with technetium-99m hexamethylpropyleneamine oxime single-photon emission computed tomography. Regional perfusion abnormalities were identified in multiple locations, particularly in the left frontal lobe. This information was used to direct an open brain biopsy, which led to a diagnosis of Creutzfeldt-Jacob disease.


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