American Journal of Neuroradiology, Vol 19, Issue 3 465-468, Copyright © 1998 by American Society of Neuroradiology
ARTICLES |
MR of hippocampal sclerosis: comparison of qualitative and quantitative assessments
JE Cheon, KH Chang, HD Kim, MH Han, SH Hong, SO Seong, IO Kim, SG Lee, YS Hwang and HJ Kim
Department of Diagnostic Radiology, Seoul National University College of Medicine, Korea.
PURPOSE: Our goal was to compare the diagnostic accuracy of subjective visual assessment versus MR volumetry in evaluating hippocampal sclerosis and to determine whether MR volumetry is needed in the lateralization of this disease process. METHODS: MR imaging findings were studied retrospectively in 48 patients who underwent surgery for temporal lobe epilepsy and were compared with findings at MR volumetry on an Allegro workstation. Both visual assessment and volumetry were carried out in a blinded fashion with oblique coronal T1-weighted three- dimensional MP-RAGE images obtained on either 1.0-T or 1.5-T units. Normal right-left volumetric differences were recorded in 30 control subjects. The optimum cutoff threshold value for right-left volumetric differences in the sensitivity and specificity of volumetric measurement was obtained from receiver operating characteristic analysis. RESULTS: Sensitivity, specificity, positive and negative predictive values, and accuracy of visual assessment were 86%, 83%, 86%, 83%, and 85%, respectively. For MR volumetry, with the optimum cutoff threshold value of right-left difference at 0.3 cm3, sensitivity, specificity, positive and negative predictive values, and accuracy were 81%, 82%, 87%, 83%, and 85%, respectively. CONCLUSION: Visual assessment was slightly superior to or similar to MR volumetry in assessing unilateral hippocampal sclerosis. MR volumetry of the hippocampus may not be needed for the evaluation of most cases of suspected hippocampal sclerosis.
This article has been cited by other articles:
 |
|
 |
|
  M. Hanamiya, Y. Korogi, S. Kakeda, N. Ohnari, K. Kamada, J. Moriya, T. Sato, M. Kitajima, N. Akamatsu, and S. Tsuji Partial Loss of Hippocampal Striation in Medial Temporal Lobe Epilepsy: Pilot Evaluation with High-Spatial-Resolution T2-weighted MR Imaging at 3.0 T Radiology, June 1, 2009; 251(3): 873 - 881. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J von Oertzen, H Urbach, S Jungbluth, M Kurthen, M Reuber, G Fernandez, and C E Elger Standard magnetic resonance imaging is inadequate for patients with refractory focal epilepsy J. Neurol. Neurosurg. Psychiatry, December 1, 2002; 73(6): 643 - 647. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Rosenow and H. Luders Presurgical evaluation of epilepsy Brain, September 1, 2001; 124(9): 1683 - 1700. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A Colchester, D Kingsley, D Lasserson, B Kendall, F Bello, C Rush, T G Stevens, G Goodman, G Heilpern, N Stanhope, et al. Structural MRI volumetric analysis in patients with organic amnesia, 1: methods and comparative findings across diagnostic groups J. Neurol. Neurosurg. Psychiatry, July 1, 2001; 71(1): 13 - 22. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S.-W. Park, K.-H. Chang, H.-D. Kim, I. C. Song, D. S. Lee, S. K. Lee, C.-K. Chung, I. K. Yu, M. H. Han, and Y. H. Park Lateralizing Ability of Single-voxel Proton MR Spectroscopy in Hippocampal Sclerosis: Comparison with MR Imaging and Positron Emission Tomography AJNR Am. J. Neuroradiol., April 1, 2001; 22(4): 625 - 631. [Abstract] [Full Text]
|
|
|
|
|
|
R. I. Grossman BRAIN IMAGING AJNR Am. J. Neuroradiol., January 1, 2000; 21(1): 9 - 18. [Full Text] [PDF]
|
|