American Journal of Neuroradiology, Vol 19, Issue 4 695-700, Copyright © 1998 by American Society of Neuroradiology
REVIEWS |
The size of lymph nodes in the neck on sonograms as a radiologic criterion for metastasis: how reliable is it?
MW van den Brekel, JA Castelijns and GB Snow
Department of Otorhinolaryngology, Free University Hospital, Amsterdam, The Netherlands.
PURPOSE: A definition of cut-off points for nodal size is essential to determine whether cervical lymph nodes are metastatic or not. Because the currently used size criteria are defined for random populations of patients with head and neck cancer, we set out to study whether these criteria are optimal for patients without palpable metastases in different levels of the neck We defined optimal size criteria for sonography by calculating the sensitivity and specificity of different size cut-off points. METHODS: We compared the sensitivity and specificity of different size cut-off points as measured on sonograms for various levels in the neck in a series of 117 patients with and 131 patients without palpable neck metastases. RESULTS: A minimum axial diameter of 7 mm for level II and 6 mm for the rest of the neck revealed the optimal compromise between sensitivity and specificity in necks without palpable metastases. For all necks together (with and without palpable metastases), the criteria were 1 to 2 mm larger. CONCLUSION: Our findings indicate that the current sonographic size criteria used for random patient populations are not optimal for necks without palpable metastases, nor can the same cut-off points be used for all levels in the neck.
This article has been cited by other articles:
![]() |
J. S. Park, K.-R. Son, D. G. Na, E. Kim, and S. Kim Performance of Preoperative Sonographic Staging of Papillary Thyroid Carcinoma Based on the Sixth Edition of the AJCC/UICC TNM Classification System Am. J. Roentgenol., January 1, 2009; 192(1): 66 - 72. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Alam, K. Naito, J. Horiguchi, H. Fukuda, T. Tachikake, and K. Ito Accuracy of Sonographic Elastography in the Differential Diagnosis of Enlarged Cervical Lymph Nodes: Comparison with Conventional B-Mode Sonography Am. J. Roentgenol., August 1, 2008; 191(2): 604 - 610. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Leboulleux, E. Girard, M. Rose, J. P. Travagli, N. Sabbah, B. Caillou, D. M. Hartl, N. Lassau, E. Baudin, and M. Schlumberger Ultrasound Criteria of Malignancy for Cervical Lymph Nodes in Patients Followed Up for Differentiated Thyroid Cancer J. Clin. Endocrinol. Metab., September 1, 2007; 92(9): 3590 - 3594. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Lyshchik, T. Higashi, R. Asato, S. Tanaka, J. Ito, M. Hiraoka, M. F. Insana, A. B. Brill, T. Saga, and K. Togashi Cervical Lymph Node Metastases: Diagnosis at Sonoelastography--Initial Experience Radiology, April 1, 2007; 243(1): 258 - 267. [Abstract] [Full Text] [PDF] |
||||
![]() |
K S S Bhatia, T Iyngkaran, and P S Richards Imaging of palpable masses in the head and neck: a practical approach using high resolution ultrasound Imaging, March 1, 2007; 19(1): 1 - 13. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. K. Kuna, I. Bracic, V. Tesic, K. Kuna, G. H. Herceg, and D. Dodig Ultrasonographic Differentiation of Benign From Malignant Neck Lymphadenopathy in Thyroid Cancer. J. Ultrasound Med., December 1, 2006; 25(12): 1531 - 1537. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Kawai, M. Sumi, and T. Nakamura Turbo Short {tau} Inversion Recovery Imaging for Metastatic Node Screening in Patients with Head and Neck Cancer AJNR Am. J. Neuroradiol., June 1, 2006; 27(6): 1283 - 1287. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. W. S. Rosario, S. de Faria, L. Bicalho, M. F. G. Alves, M. A. R. Borges, S. Purisch, E. L. Padrao, L. L. Rezende, and A. L. Barroso Ultrasonographic Differentiation Between Metastatic and Benign Lymph Nodes in Patients With Papillary Thyroid Carcinoma J. Ultrasound Med., October 1, 2005; 24(10): 1385 - 1389. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. W. S. do Rosario, T. A. Fagundes, F. F. R. Maia, A. C. H. M. Franco, M. B. Figueiredo, and S. Purisch Sonography in the Diagnosis of Cervical Recurrence in Patients With Differentiated Thyroid Carcinoma J. Ultrasound Med., July 1, 2004; 23(7): 915 - 920. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Sumi, N. Sakihama, T. Sumi, M. Morikawa, M. Uetani, H. Kabasawa, K. Shigeno, K. Hayashi, H. Takahashi, and T. Nakamura Discrimination of Metastatic Cervical Lymph Nodes with Diffusion-Weighted MR Imaging in Patients with Head and Neck Cancer AJNR Am. J. Neuroradiol., September 1, 2003; 24(8): 1627 - 1634. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Anzai, C. W. Piccoli, E. K. Outwater, W. Stanford, D. A. Bluemke, P. Nurenberg, S. Saini, K. R. Maravilla, D. E. Feldman, U. P. Schmiedl, et al. Evaluation of Neck and Body Metastases to Nodes with Ferumoxtran 10-enhanced MR Imaging: Phase III Safety and Efficacy Study Radiology, September 1, 2003; 228(3): 777 - 788. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. To, W. Tsang, J Cheng, E Lai, P Pang, A. Ahuja, and M Ying Is neck ultrasound necessary for early stage oral tongue carcinoma with clinically N0 neck? Dentomaxillofac. Radiol., May 1, 2003; 32(3): 156 - 159. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Eida, M. Sumi, K. Yonetsu, Y. Kimura, and T. Nakamura Combination of Helical CT and Doppler Sonography in the Follow-up of Patients with Clinical N0 Stage Neck Disease and Oral Cancer AJNR Am. J. Neuroradiol., March 1, 2003; 24(3): 312 - 318. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. J. Screaton, L. H. Berman, and J. W. Grant Head and Neck Lymphadenopathy: Evaluation with US-guided Cutting-Needle Biopsy Radiology, July 1, 2002; 224(1): 75 - 81. [Abstract] [Full Text] |
||||
![]() |
M. Sumi, M. Ohki, and T. Nakamura Comparison of Sonography and CT for Differentiating Benign from Malignant Cervical Lymph Nodes in Patients with Squamous Cell Carcinoma of the Head and Neck Am. J. Roentgenol., April 1, 2001; 176(4): 1019 - 1024. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Yonetsu, M. Sumi, M. Izumi, M. Ohki, S. Eida, and T. Nakamura Contribution of Doppler Sonography Blood Flow Information to the Diagnosis of Metastatic Cervical Nodes in Patients with Head and Neck Cancer: Assessment in Relation to Anatomic Levels of the Neck AJNR Am. J. Neuroradiol., January 1, 2001; 22(1): 163 - 169. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Chikui, K. Yonetsu, and T. Nakamura Multivariate Feature Analysis of Sonographic Findings of Metastatic Cervical Lymph Nodes: Contribution of Blood Flow Features Revealed by Power Doppler Sonography for Predicting Metastasis AJNR Am. J. Neuroradiol., March 1, 2000; 21(3): 561 - 567. [Abstract] [Full Text] |
||||
![]() |
M. W.M. van den Brekel, L. C. Reitsma, J. J. Quak, L. E. Smeele, J. C, v. d. Linden, G. B. Snow, and J. A. Castelijns Sonographically Guided Aspiration Cytology of Neck Nodes for Selection of Treatment and Follow-up in Patients with N0 Head and Neck Cancer AJNR Am. J. Neuroradiol., October 1, 1999; 20(9): 1727 - 1731. [Abstract] [Full Text] |
||||
![]() |
M. G. Mack, J. O. Balzer, R. Straub, K. Eichler, and T. J. Vogl Superparamagnetic Iron Oxide-enhanced MR Imaging of Head and Neck Lymph Nodes Radiology, January 1, 2002; 222(1): 239 - 244. [Abstract] [Full Text] [PDF] |
||||






