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American Journal of Neuroradiology, Vol 19, Issue 5 894-896, Copyright © 1998 by American Society of Neuroradiology

ARTICLES

Myelopathy caused by nitrous oxide toxicity

PJ Pema, HA Horak and RH Wyatt
Department of Radiology, Ohio State University Medical Center, Columbus, USA.

We describe a case of myeloneuropathy resulting from nitrous oxide abuse. MR imaging of the spine revealed symmetric abnormal signal in the posterior columns of the cervical cord. Myeloneuropathy is caused by inactivation of vitamin B12 by nitrous oxide. This syndrome can also be seen in patients with borderline vitamin B12 deficiency who have recently been anesthetized with nitrous oxide.


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Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X