American Journal of Neuroradiology, Vol 19, Issue 6 1061-1066, Copyright © 1998 by American Society of Neuroradiology
ARTICLES |
Clinical experience with diffusion-weighted MR in patients with acute stroke
KO Lovblad, HJ Laubach, AE Baird, F Curtin, G Schlaug, RR Edelman and S Warach
Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass, USA.
PURPOSE: Our purpose was to evaluate the clinical efficacy, sensitivity, and specificity of echo-planar diffusion-weighted MR imaging in patients with acute infarction. METHODS: We retrospectively analyzed 194 cases of acute ischemic stroke diagnosed clinically within 24 hours of onset and studied with echo-planar diffusion-weighted MR imaging. Examinations were considered to be positive for infarction when an increase in signal was noted on images acquired at a high b value but absent on images with a low b value. A final clinical diagnosis of acute stroke was used as the standard of reference. A subset of 48 patients scanned within 6 hours was also analyzed. RESULTS: Diffusion-weighted MR imaging studies were positive in 133 of 151 cases of infarction (88% sensitivity) and negative in 41 of 43 cases with no infarction (95% specificity). Two cases identified as positive on diffusion-weighted images had nonischemic diagnoses (1.5% false-positive rate). Diffusion-weighted imaging had a positive predictive value of 98.5% and a negative predictive value of 69.5%. Use of T2-weighted sequences as well as diffusion-weighted imaging produced no false-positive findings. Of the negative scans, 69.5% corresponded to transient ischemic attacks or infarcts (mostly small brain stem infarcts). When only cases scanned within 6 hours of onset were considered, the sensitivity rose to 94% and the specificity to 100%. CONCLUSION: Despite bias due to dependence between diffusion-weighted imaging and the final diagnosis, this analysis suggests high sensitivity and specificity for echo-planar diffusion-weighted imaging in the diagnosis of acute cerebral infarction, although negative scans did not rule out an ischemic pathogenesis.
This article has been cited by other articles:
![]() |
P.G. Kranz and J.D. Eastwood Does Diffusion-Weighted Imaging Represent the Ischemic Core? An Evidence-Based Systematic Review AJNR Am. J. Neuroradiol., June 1, 2009; 30(6): 1206 - 1212. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. S. Roach, M. R. Golomb, R. Adams, J. Biller, S. Daniels, G. deVeber, D. Ferriero, B. V. Jones, F. J. Kirkham, R. M. Scott, et al. Management of Stroke in Infants and Children: A Scientific Statement From a Special Writing Group of the American Heart Association Stroke Council and the Council on Cardiovascular Disease in the Young Stroke, September 1, 2008; 39(9): 2644 - 2691. [Abstract] [Full Text] [PDF] |
||||
![]() |
P.N. Sylaja, S. B. Coutts, A. Krol, M. D. Hill, A. M. Demchuk, and for the VISION Study Group When to Expect Negative Diffusion-Weighted Images in Stroke and Transient Ischemic Attack Stroke, June 1, 2008; 39(6): 1898 - 1900. [Abstract] [Full Text] [PDF] |
||||
![]() |
J.-M. Boulanger, S. B. Coutts, M. Eliasziw, S. Subramaniam, J. Scott, and A. M. Demchuk Diffusion-Weighted Imaging-Negative Patients With Transient Ischemic Attack Are at Risk of Recurrent Transient Events Stroke, August 1, 2007; 38(8): 2367 - 2369. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. P. Adams Jr, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, et al. Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Circulation, May 22, 2007; 115(20): e478 - e534. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. P. Adams Jr, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, et al. Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/ American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists Stroke, May 1, 2007; 38(5): 1655 - 1711. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Srinivasan, M. Goyal, F. A. Azri, and C. Lum State-of-the-Art Imaging of Acute Stroke RadioGraphics, October 1, 2006; 26(suppl_1): S75 - S95. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Pinero, A. Gonzalez, A. Mayol, E. Martinez, J.R. Gonzalez-Marcos, F. Boza, A. Cayuela, and A. Gil-Peralta Silent Ischemia after Neuroprotected Percutaneous Carotid Stenting: A Diffusion-Weighted MRI Study AJNR Am. J. Neuroradiol., June 1, 2006; 27(6): 1338 - 1345. [Abstract] [Full Text] [PDF] |
||||
![]() |
R.G. Gonzalez Imaging-guided acute ischemic stroke therapy: From "time is brain" to "physiology is brain". AJNR Am. J. Neuroradiol., April 1, 2006; 27(4): 728 - 735. [Abstract] [Full Text] [PDF] |
||||
![]() |
P L Tan, D King, C J Durkin, T M Meagher, and D Briley Diffusion weighted magnetic resonance imaging for acute stroke: practical and popular. Postgrad. Med. J., April 1, 2006; 82(966): 289 - 292. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Maeda, H. Kato, H. Sakuma, S. E. Maier, and K. Takeda Usefulness of the Apparent Diffusion Coefficient in Line Scan Diffusion-Weighted Imaging for Distinguishing between Squamous Cell Carcinomas and Malignant Lymphomas of the Head and Neck AJNR Am. J. Neuroradiol., May 1, 2005; 26(5): 1186 - 1192. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. J. Kim, C. G. Choi, D. H. Lee, J. H. Lee, S. J. Kim, and D. C. Suh High-b-Value Diffusion-Weighted MR Imaging of Hyperacute Ischemic Stroke at 1.5T AJNR Am. J. Neuroradiol., February 1, 2005; 26(2): 208 - 215. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. G. Roh, H. S. Byun, J. W. Ryoo, D. G. Na, W.-J. Moon, B. B. Lee, and D.-I. Kim Prospective Analysis of Cerebral Infarction After Carotid Endarterectomy and Carotid Artery Stent Placement by Using Diffusion-Weighted Imaging AJNR Am. J. Neuroradiol., February 1, 2005; 26(2): 376 - 384. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. K. Kuhl, J. Gieseke, M. von Falkenhausen, J. Textor, S. Gernert, C. Sonntag, and H. H. Schild Sensitivity Encoding for Diffusion-weighted MR Imaging at 3.0 T: Intraindividual Comparative Study Radiology, February 1, 2005; 234(2): 517 - 526. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. K. Kuhl, J. Textor, J. Gieseke, M. von Falkenhausen, S. Gernert, H. Urbach, and H. H. Schild Acute and Subacute Ischemic Stroke at High-Field-Strength (3.0-T) Diffusion-weighted MR Imaging: Intraindividual Comparative Study Radiology, February 1, 2005; 234(2): 509 - 516. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. P. Kloska, D. G. Nabavi, C. Gaus, E.-M. Nam, E. Klotz, E. B. Ringelstein, and W. Heindel Acute Stroke Assessment with CT: Do We Need Multimodal Evaluation? Radiology, October 1, 2004; 233(1): 79 - 86. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Duning, A. Rogalewski, O. Steinstraeter, H. Kugel, A. Jansen, C. Breitenstein, S. Knecht, F. M. Mottaghy, A. Pascual-Leone, and G. Schlaug Repetitive TMS temporarily alters brain diffusion Neurology, June 8, 2004; 62(11): 2144 - 2145. [Full Text] |
||||
![]() |
P. W. Schaefer, A. Hassankhani, C. Putman, A. G. Sorensen, L. Schwamm, W. Koroshetz, and R. G. Gonzalez Characterization and Evolution of Diffusion MR Imaging Abnormalities in Stroke Patients Undergoing Intra-Arterial Thrombolysis AJNR Am. J. Neuroradiol., June 1, 2004; 25(6): 951 - 957. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Ozsunar, P. E. Grant, T. A. G. M. Huisman, P. W. Schaefer, O. Wu, A. G. Sorensen, W. J. Koroshetz, and R. G. Gonzalez Evolution of Water Diffusion and Anisotropy in Hyperacute Stroke: Significant Correlation between Fractional Anisotropy and T2 AJNR Am. J. Neuroradiol., May 1, 2004; 25(5): 699 - 705. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. T. Engelter, S. G. Wetzel, E. W. Radue, M. Rausch, A. J. Steck, and P. A. Lyrer The clinical significance of diffusion-weighted MR imaging in infratentorial strokes Neurology, February 24, 2004; 62(4): 574 - 580. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Warach and C. S. Kidwell The redefinition of TIA: The uses and limitations of DWI in acute ischemic cerebrovascular syndromes Neurology, February 10, 2004; 62(3): 359 - 360. [Full Text] [PDF] |
||||
![]() |
D. Saur, T. Kucinski, U. Grzyska, B. Eckert, C. Eggers, W. Niesen, V. Schoder, H. Zeumer, C. Weiller, and J. Rother Sensitivity and Interrater Agreement of CT and Diffusion-Weighted MR Imaging in Hyperacute Stroke AJNR Am. J. Neuroradiol., May 1, 2003; 24(5): 878 - 885. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. P. Adams Jr, R. J. Adams, T. Brott, G. J. del Zoppo, A. Furlan, L. B. Goldstein, R. L. Grubb, R. Higashida, C. Kidwell, T. G. Kwiatkowski, et al. Guidelines for the Early Management of Patients With Ischemic Stroke: A Scientific Statement From the Stroke Council of the American Stroke Association Stroke, April 1, 2003; 34(4): 1056 - 1083. [Full Text] [PDF] |
||||
![]() |
R. E. Latchaw, H. Yonas, G. J. Hunter, W. T.C. Yuh, T. Ueda, A. G. Sorensen, J. L. Sunshine, J. Biller, L. Wechsler, R. Higashida, et al. Guidelines and Recommendations for Perfusion Imaging in Cerebral Ischemia: A Scientific Statement for Healthcare Professionals by the Writing Group on Perfusion Imaging, From the Council on Cardiovascular Radiology of the American Heart Association Stroke, April 1, 2003; 34(4): 1084 - 1104. [Full Text] [PDF] |
||||
![]() |
R. A. Crisostomo, M. M. Garcia, and D. C. Tong Detection of Diffusion-Weighted MRI Abnormalities in Patients With Transient Ischemic Attack: Correlation With Clinical Characteristics Stroke, April 1, 2003; 34(4): 932 - 937. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Macdonald and P. A Gaines Current concepts of mechanical cerebral protection during precutaneous carotid intervention Vascular Medicine, February 1, 2003; 8(1): 25 - 32. [Abstract] [PDF] |
||||
![]() |
T. W. Stadnik, P. Demaerel, R. R Luypaert, C. Chaskis, K. L. Van Rompaey, A. Michotte, and M. J. Osteaux Imaging Tutorial: Differential Diagnosis of Bright Lesions on Diffusion-weighted MR Images RadioGraphics, January 1, 2003; 23(1): e7 - e7. [Abstract] [Full Text] |
||||
![]() |
P. W. Schaefer, G. J. Hunter, J. He, L. M. Hamberg, A. G. Sorensen, L. H. Schwamm, W. J. Koroshetz, and R. G. Gonzalez Predicting Cerebral Ischemic Infarct Volume with Diffusion and Perfusion MR Imaging AJNR Am. J. Neuroradiol., November 1, 2002; 23(10): 1785 - 1794. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. R. Melhem Time-course of apparent diffusion coefficient in neonatal brain injury: The first piece of the puzzle Neurology, September 24, 2002; 59(6): 798 - 799. [Full Text] [PDF] |
||||
![]() |
J. F. Arenillas, A. Rovira, C. A. Molina, E. Grive, J. Montaner, J. Alvarez-Sabin, and K.-O. Lovblad Prediction of Early Neurological Deterioration Using Diffusion- and Perfusion-Weighted Imaging in Hyperacute Middle Cerebral Artery Ischemic Stroke * Editorial Comment Stroke, September 1, 2002; 33(9): 2197 - 2205. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. E. Mullins, P. W. Schaefer, A. G. Sorensen, E. F. Halpern, H. Ay, J. He, W. J. Koroshetz, and R. G. Gonzalez CT and Conventional and Diffusion-weighted MR Imaging in Acute Stroke: Study in 691 Patients at Presentation to the Emergency Department Radiology, August 1, 2002; 224(2): 353 - 360. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. C. Guo, T. J. Cummings, R. C. Dash, and J. M. Provenzale Lymphomas and High-Grade Astrocytomas: Comparison of Water Diffusibility and Histologic Characteristics Radiology, July 1, 2002; 224(1): 177 - 183. [Abstract] [Full Text] |
||||
![]() |
J J Marx, A Mika-Gruettner, F Thoemke, S Fitzek, C Fitzek, G Vucurevic, P P Urban, P Stoeter, and H C Hopf Diffusion weighted magnetic resonance imaging in the diagnosis of reversible ischaemic deficits of the brainstem J. Neurol. Neurosurg. Psychiatry, May 1, 2002; 72(5): 572 - 575. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. J. Jaeger, K. D. Mathias, E. Hauth, R. Drescher, H. M. Gissler, S. Hennigs, and A. Christmann Cerebral Ischemia Detected with Diffusion-Weighted MR Imaging after Stent Implantation in the Carotid Artery AJNR Am. J. Neuroradiol., February 1, 2002; 23(2): 200 - 207. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Rovira, A. Rovira-Gols, S. Pedraza, E. Grive, C. Molina, and J. Alvarez-Sabin Diffusion-Weighted MR Imaging in the Acute Phase of Transient Ischemic Attacks AJNR Am. J. Neuroradiol., January 1, 2002; 23(1): 77 - 83. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. A. Copen, L. H. Schwamm, R. G. Gonzalez, O. Wu, C. B. Harmath, P. W. Schaefer, W. J. Koroshetz, and A. G. Sorensen Ischemic Stroke: Effects of Etiology and Patient Age on the Time Course of the Core Apparent Diffusion Coefficient Radiology, October 1, 2001; 221(1): 27 - 34. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. E. Grant, J. He, E. F. Halpern, O. Wu, P. W. Schaefer, L. H. Schwamm, R. F. Budzik, A. G. Sorensen, W. J. Koroshetz, and R. G. Gonzalez Frequency and Clinical Context of Decreased Apparent Diffusion Coefficient Reversal in the Human Brain Radiology, October 1, 2001; 221(1): 43 - 50. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Warach New imaging strategies for patient selection for thrombolytic and neuroprotective therapies Neurology, September 1, 2001; 57(90002): S48 - 52. [Abstract] [Full Text] |
||||
![]() |
H. J. Jaeger, K. D. Mathias, R. Drescher, E. Hauth, G. Bockisch, E. Demirel, and H. Martin Gissler Diffusion-weighted MR Imaging After Angioplasty or Angioplasty Plus Stenting of Arteries Supplying the Brain AJNR Am. J. Neuroradiol., August 1, 2001; 22(7): 1251 - 1259. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. L. Sunshine, N. Bambakidis, R. W. Tarr, C. F. Lanzieri, O. O. Zaidat, J. I. Suarez, D. M.D. Landis, and W. R. Selman Benefits of Perfusion MR Imaging Relative to Diffusion MR Imaging in the Diagnosis and Treatment of Hyperacute Stroke AJNR Am. J. Neuroradiol., May 1, 2001; 22(5): 915 - 921. [Abstract] [Full Text] |
||||
![]() |
T. W. Stadnik, C. Chaskis, A. Michotte, W. M. Shabana, K. van Rompaey, R. Luypaert, L. Budinsky, V. Jellus, and M. Osteaux Diffusion-weighted MR Imaging of Intracerebral Masses: Comparison with Conventional MR Imaging and Histologic Findings AJNR Am. J. Neuroradiol., May 1, 2001; 22(5): 969 - 976. [Abstract] [Full Text] |
||||
![]() |
C. B. Grandin, T. P. Duprez, A. M. Smith, F. Mataigne, A. Peeters, C. Oppenheim, and G. Cosnard Usefulness of Magnetic Resonance-Derived Quantitative Measurements of Cerebral Blood Flow and Volume in Prediction of Infarct Growth in Hyperacute Stroke Stroke, May 1, 2001; 32(5): 1147 - 1153. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Maeda, T. Yamamoto, S. Daimon, H. Sakuma, and K. Takeda Arterial Hyperintensity on Fast Fluid-attenuated Inversion Recovery Images: A Subtle Finding for Hyperacute Stroke Undetected by Diffusion-weighted MR Imaging AJNR Am. J. Neuroradiol., April 1, 2001; 22(4): 632 - 636. [Abstract] [Full Text] |
||||
![]() |
M. G. Lansberg, V. N. Thijs, M. W. O'Brien, J. O. Ali, A. J. de Crespigny, D. C. Tong, M. E. Moseley, and G. W. Albers Evolution of Apparent Diffusion Coefficient, Diffusion-weighted, and T2-weighted Signal Intensity of Acute Stroke AJNR Am. J. Neuroradiol., April 1, 2001; 22(4): 637 - 644. [Abstract] [Full Text] |
||||
![]() |
O. Wu, W. J. Koroshetz, L. Ostergaard, F. S. Buonanno, W. A. Copen, R. G. Gonzalez, G. Rordorf, B. R. Rosen, L. H. Schwamm, R. M. Weisskoff, et al. Predicting Tissue Outcome in Acute Human Cerebral Ischemia Using Combined Diffusion- and Perfusion-Weighted MR Imaging Stroke, April 1, 2001; 32(4): 933 - 942. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Pantano, D. Toni, F. Caramia, A. Falcou, M. Fiorelli, C. Argentino, L. M. Fantozzi, and L. Bozzao Relationship between Vascular Enhancement, Cerebral Hemodynamics, and MR Angiography in Cases of Acute Stroke AJNR Am. J. Neuroradiol., February 1, 2001; 22(2): 255 - 260. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Back, J. G. Hirsch, K. Szabo, and A. Gass Failure to Demonstrate Peri-Infarct Depolarizations by Repetitive MR Diffusion Imaging in Acute Human Stroke Stroke, December 1, 2000; 31(12): 2901 - 2906. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. R. Meyer, A. Gutierrez, B. Mock, D. Hebron, J. M. Prager, M. T. Gorey, and D. Homer High-b-value Diffusion-weighted MR Imaging of Suspected Brain Infarction AJNR Am. J. Neuroradiol., November 1, 2000; 21(10): 1821 - 1829. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. W. Schaefer, P. E. Grant, and R. G. Gonzalez Diffusion-weighted MR Imaging of the Brain Radiology, November 1, 2000; 217(2): 331 - 345. [Abstract] [Full Text] |
||||
![]() |
S. L. Keir and J. M. Wardlaw Systematic Review of Diffusion and Perfusion Imaging in Acute Ischemic Stroke Stroke, November 1, 2000; 31(11): 2723 - 2731. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Augustin, R. Bammer, J. Simbrunner, R. Stollberger, H.-P. Hartung, and F. Fazekas Diffusion-weighted Imaging of Patients with Subacute Cerebral Ischemia: Comparison with Conventional and Contrast-enhanced MR Imaging AJNR Am. J. Neuroradiol., October 1, 2000; 21(9): 1596 - 1602. [Abstract] [Full Text] |
||||
![]() |
K. S. Krishnamoorthy, T. B. Soman, M. Takeoka, and P. W. Schaefer Diffusion-Weighted Imaging in Neonatal Cerebral Infarction: Clinical Utility and Follow-Up J Child Neurol, September 1, 2000; 15(9): 592 - 602. [Abstract] [PDF] |
||||
![]() |
M. G. Lansberg, A. M. Norbash, M. P. Marks, D. C. Tong, M. E. Moseley, and G. W. Albers Advantages of Adding Diffusion-Weighted Magnetic Resonance Imaging to Conventional Magnetic Resonance Imaging for Evaluating Acute Stroke Arch Neurol, September 1, 2000; 57(9): 1311 - 1316. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Oppenheim, Y. Samson, R. Manai, T. Lalam, X. Vandamme, S. Crozier, A. Srour, P. Cornu, D. Dormont, G. Rancurel, et al. Prediction of Malignant Middle Cerebral Artery Infarction by Diffusion-Weighted Imaging Stroke, September 1, 2000; 31(9): 2175 - 2181. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Oppenheim, R. Stanescu, D. Dormont, S. Crozier, B. Marro, Y. Samson, G. Rancurel, and C. Marsault False-negative Diffusion-weighted MR Findings in Acute Ischemic Stroke AJNR Am. J. Neuroradiol., August 1, 2000; 21(8): 1434 - 1440. [Abstract] [Full Text] |
||||
![]() |
K. P. N. Forbes, J. G. Pipe, and R. Bird Neonatal Hypoxic-ischemic Encephalopathy: Detection with Diffusion-weighted MR Imaging AJNR Am. J. Neuroradiol., August 1, 2000; 21(8): 1490 - 1496. [Abstract] [Full Text] |
||||
![]() |
A. Barth, L. Remonda, K.-O. Lovblad, G. Schroth, and R. W. Seiler Silent Cerebral Ischemia Detected by Diffusion-Weighted MRI After Carotid Endarterectomy Stroke, August 1, 2000; 31(8): 1824 - 1828. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. D Schellinger, O. Jansen, J. B Fiebach, O. Pohlers, H. Ryssel, S. Heiland, T. Steiner, W. Hacke and, and K. Sartor Feasibility and Practicality of MR Imaging of Stroke in the Management of Hyperacute Cerebral Ischemia AJNR Am. J. Neuroradiol., July 1, 2000; 21(7): 1184 - 1189. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Oliveira-Filho, H. Ay, P. W. Schaefer, F. S. Buonanno, Y. Chang, R. G. Gonzalez, and W. J. Koroshetz Diffusion-Weighted Magnetic Resonance Imaging Identifies the "Clinically Relevant" Small-Penetrator Infarcts Arch Neurol, July 1, 2000; 57(7): 1009 - 1014. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Biondi, C. Oppenheim, E. Vivas, A. Casasco, T. Lalam, N. Sourour, L. L. Jean, D. Dormont, and C. Marsault Cerebral Aneurysms Treated by Guglielmi Detachable Coils: Evaluation with Diffusion-weighted MR Imaging AJNR Am. J. Neuroradiol., May 1, 2000; 21(5): 957 - 963. [Abstract] [Full Text] |
||||
![]() |
W. Hacke and S. Warach Diffusion-weighted MRI as an evolving standard of care in acute stroke Neurology, April 25, 2000; 54(8): 1548 - 1549. [Full Text] [PDF] |
||||
![]() |
G. W. Albers, M. G. Lansberg, A. M. Norbash, D. C. Tong, M. W. O'Brien, A. R. Woolfenden, M. P. Marks, and M. E. Moseley Yield of diffusion-weighted MRI for detection of potentially relevant findings in stroke patients Neurology, April 25, 2000; 54(8): 1562 - 1567. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. J. Quint Indications for Emergent MRI of the Central Nervous System JAMA, February 16, 2000; 283(7): 853 - 855. [Full Text] [PDF] |
||||
![]() |
M. Muller, W. Reiche, P. Langenscheidt, J. Ha{beta}feld, and T. Hagen Ischemia after Carotid Endarterectomy: Comparison between Transcranial Doppler Sonography and Diffusion-Weighted MR Imaging AJNR Am. J. Neuroradiol., January 1, 2000; 21(1): 47 - 54. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. M. Britt, J. E. Heiserman, R. M. Snider, H. A. Shill, C. R. Bird, and R. C. Wallace Incidence of Postangiographic Abnormalities Revealed by Diffusion-Weighted MR Imaging AJNR Am. J. Neuroradiol., January 1, 2000; 21(1): 55 - 59. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Grond, R. von Kummer, J. Sobesky, S. Schmulling, J. Rudolf, K. Terstegge, and W.-D. Heiss Early X-Ray Hypoattenuation of Brain Parenchyma Indicates Extended Critical Hypoperfusion in Acute Stroke Stroke, January 1, 2000; 31(1): 133 - 139. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. T. C. Yuh, T. Ueda, M. White, M. E. Schuster, and T. Taoka The Need for Objective Assessment of the New Imaging Techniques and Understanding the Expanding Roles of Stroke Imaging AJNR Am. J. Neuroradiol., November 1, 1999; 20(10): 1779 - 1784. [Full Text] |
||||
![]() |
J. R. Reichenbach, J. Röther, L. Jonetz-Mentzel, M. Herzau, A. Fiala, C. Weiller, and W. A. Kaiser Acute Stroke Evaluated by Time-to-Peak Mapping during Initial and Early Follow-up Perfusion CT Studies AJNR Am. J. Neuroradiol., November 1, 1999; 20(10): 1842 - 1850. [Abstract] [Full Text] |
||||
![]() |
D. Lefkowitz, M. LaBenz, S. R. Nudo, R. E. Steg, and J. M. Bertoni Hyperacute Ischemic Stroke Missed by Diffusion-Weighted Imaging AJNR Am. J. Neuroradiol., November 1, 1999; 20(10): 1871 - 1875. [Abstract] [Full Text] |
||||
![]() |
P. Y-K. Wang, P. B. Barker, R. J. Wityk, A. M. Ulug, P. C. M. van Zijl, and N. J. Beauchamp Diffusion-Negative Stroke: A Report of Two Cases AJNR Am. J. Neuroradiol., November 1, 1999; 20(10): 1876 - 1880. [Abstract] [Full Text] |
||||
![]() |
P. A. Barber, D. G. Darby, P. M. Desmond, R. P. Gerraty, Q. Yang, T. Li, D. Jolley, G. A. Donnan, B. M. Tress, and S. M. Davis Identification of Major Ischemic Change : Diffusion-Weighted Imaging Versus Computed Tomography Stroke, October 1, 1999; 30(10): 2059 - 2065. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Desprechins, T. Stadnik, G. Koerts, W. Shabana, C. Breucq, and M. Osteaux Use of Diffusion-Weighted MR Imaging in Differential Diagnosis Between Intracerebral Necrotic Tumors and Cerebral Abscesses AJNR Am. J. Neuroradiol., August 1, 1999; 20(7): 1252 - 1257. [Abstract] [Full Text] |
||||
![]() |
J. L. Sunshine, R. W. Tarr, C. F. Lanzieri, D. M. D. Landis, W. R. Selman, and J. S. Lewin Hyperacute Stroke: Ultrafast MR Imaging to Triage Patients prior to Therapy Radiology, August 1, 1999; 212(2): 325 - 332. [Abstract] [Full Text] |
||||
![]() |
J. O. Karonen, R. L. Vanninen, Y. Liu, L. Ostergaard, J. T. Kuikka, J. Nuutinen, E. J. Vanninen, P. L. K. Partanen, P. A. Vainio, K. Korhonen, et al. Combined Diffusion and Perfusion MRI With Correlation to Single-Photon Emission CT in Acute Ischemic Stroke : Ischemic Penumbra Predicts Infarct Growth Stroke, August 1, 1999; 30(8): 1583 - 1590. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Ueda, W. T. C. Yuh, J. E. Maley, J. P. Quets, P. Y. Hahn, and V. A. Magnotta Outcome of Acute Ischemic Lesions Evaluated by Diffusion and Perfusion MR Imaging AJNR Am. J. Neuroradiol., June 1, 1999; 20(6): 983 - 989. [Abstract] [Full Text] |
||||
![]() |
M. G. Lansberg, D. C. Tong, A. M. Norbash, M. A. Yenari, and M. E. Moseley Intra-Arterial rtPA Treatment of Stroke Assessed by Diffusion- and Perfusion-Weighted MRI Stroke, March 1, 1999; 30(3): 678 - 680. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. E. Lecouvet, T. P. J. Duprez, J. M. Raymackers, A. Peeters, and G. Cosnard Resolution of early diffusion-weighted and FLAIR MRI abnormalities in a patient with TIA Neurology, March 1, 1999; 52(5): 1085 - 1085. [Abstract] [Full Text] |
||||











