American Journal of Neuroradiology, Vol 19, Issue 6 1123-1125, Copyright © 1998 by American Society of Neuroradiology
ARTICLES |
A canine model of acute hydrocephalus with MR correlation
T Vullo, R Manzo, DG Gomez, MD Deck and PT Cahill
Department of Radiology, The New York Hospital, Cornell University Medical College, New York 10021, USA.
Within 3 hours of induction of acute hydrocephalus in a canine model, lateral ventricular CSF pressure increased from an initial average of 14.6 +/- 2.8 cm H2O to 40.2 +/- 5.7 cm H2O. Ventricular volumes, as measured from MR images, increased 1.45 +/- 0.94 cm3, 1.92 +/- 0.82 cm3, and 2.24 +/- 0.60 cm3 after 6, 24, and 48 hours, of hydrocephalus, respectively. This canine model was reliable and consistent with clinical conditions.