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American Journal of Neuroradiology, Vol 19, Issue 8 1437-1440, Copyright © 1998 by American Society of Neuroradiology

ARTICLES

Spontaneous labyrinthine hemorrhage in sickle cell disease

RE Whitehead, CB MacDonald, ER Melhem and L McMahon
Department of Radiology, Boston Medical Center, MA 02118, USA.

We report the clinical and MR imaging findings in two African-American patients with manifestations of sickle cell disease affecting the inner ear. Both suffered sudden-onset sensorineural hearing loss and vestibular symptoms, and both had high labyrinthine signal on T1- weighted MR images attributed to labyrinthine hemorrhage. Follow-up studies of the first patient revealed a decrease in abnormal vestibular signal. Careful attention to the labyrinth on T1-weighted MR images can reveal vestibulocochlear clinical findings in sickle cell patients, with important implications for management and prognosis.




Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X