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American Journal of Neuroradiology, Vol 19, Issue 9 1636-1638, Copyright © 1998 by American Society of Neuroradiology

ARTICLES

Lasting cytotoxic edema as an indicator of irreversible brain damage: a case of neonatal stroke

H Rumpel, B Ferrini and E Martin
Division of Magnetic Resonance and Developmental Brain Research, University Children's Hospital Zurich, Switzerland.

We describe a case of neonatal stroke in the territory of the left middle cerebral artery. Although the ischemic lesion appeared rather homogeneously hyperintense on T2-weighted MR images, corresponding diffusion-weighted images clearly delineated two separate zones of different cellular swelling and, thus, different prognoses. Lasting cytotoxic edema heralded infarction. We believe that the different rates of disintegration of neurons and glial cells may have caused the change from intracellular to interstitial volume fraction during the evolution of edema.




Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X