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ARTICLE

Central Brain Herniation Secondary to JuvenileDiabetic Ketoacidosis

David A. Shrier,a, Dean K. Shibataa, Henry Z. Wanga, Yuji Numaguchia and James M. Powersa

a From the Departments of Radiology (D.A.S., D.K.S., H.Z.W., Y.N.) and Pathology and Lab Medicine (J.M.P.) University of Rochester School of Medicine and Dentistry, Strong Memorial Hospital, Rochester, NY.

Summary: We present the CT, MR, and autopsy findings of central brain herniation in a 9-year-old boy undergoing treatment for diabetic ketoacidosis (DKA). Severe cerebral edema resulting in central brain herniation is an uncommon complication of the treatment of DKA but carries with it high morbidity and mortality. Radiologic imaging and autopsy findings in this case revealed striking infarctions of central brain structures.




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