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ARTICLE

Embolization of the Meningohypophyseal Trunk as a Cause of Diabetes Insipidus

Constantine C. Phatourosa, Randall T. Higashidaa, Adel M. Maleka, Wade S. Smitha, Christopher F. Dowda and Van V. Halbacha

a From the Division of Neurointerventional Radiology (C.C.P., R.T.H., A.M.M., C.F.D., V.V.H.) and the Department of Neurology (W.S.S.), University of California at San Francisco Medical Center.

Summary: We present an unusual case of diabetes insipidus occurring after selective embolization of 50% dextrose and pure ethanol into an enlarged left meningohypophyseal trunk (MHT) supplying a dural carotid cavernous fistula. The inferior hypophyseal artery was not opacified during the selective preembolization MHT injection; however, diabetes insipidus developed abruptly a few hours after the procedure. The patient required intranasal 1-deamino-(8-D-arginine)-vasopressin for approximately 3 months, after which his symptoms resolved. The hazards of using liquid embolic agents, especially ethanol, in the cavernous branches of the internal carotid artery should always be borne in mind.




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