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ARTICLE

Radiologic-Pathologic Findings in Raccoon Roundworm (Baylisascaris procyonis) Encephalitis

Howard A. Rowley,a, Rosalie M. Uhta, Kevin R. Kazacosa, Judy Sakanaria, Wendy V. Wheatona, A. James Barkovicha and Andrew W. Bollena

a From the Departments of Neurology and Radiology (H.A.R., A.J.B.) and Pathology (R.M.U., J.S., A.W.B.), University of California, San Francisco, San Francisco, CA; the Department of Veterinary Pathobiology (K.R.K.), Purdue University, West Lafayette, IN; the Department of Biology (J.S.), Sonoma State University, Rohnert Park, CA; and the Department of Pediatrics (W.V.W.), Kaiser-Permanente Medical Center, Hayward, CA.

Summary: A 13-month-old boy developed eosinophilic meningoencephalitis, retinitis, and a protracted encephalopathy with severe residual deficits. The initial MR examination revealed diffuse periventricular white matter disease, and follow-up images showed atrophy. Brain biopsy, serology, and epidemiologic studies lead to the diagnosis of Baylisascaris procyonis infection, a parasitic disease contracted through exposure to soil contaminated by the eggs of a common raccoon intestinal roundworm. The pathologic, epidemiologic, and imaging features of this disease are herein reviewed.




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