AJDRAJNR - American Journal of Neuroradiology

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ARTICLE

Dedifferentiated Chondrosarcoma of the Larynx

Osamu Sakai a, Hugh D. Curtin ,a, William C. Faquin a and Richard L. Fabian a

a From the Departments of Radiology (O.S., H.D.C.), Pathology (W.C.F.), and Head and Neck Surgery (R.L.F.), Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA.

Summary: A 74-year-old man with a history of a chondroid lesion of the larynx noted an enlarging neck mass. Axial CT showed a large expansile lesion arising from the left thyroid cartilage. Multiple rings and arcs with relatively intact cortex indicated a chondroid lesion. Irregularity of the anterolateral margin abutted a prominent soft-tissue component. The specimen obtained from fine needle aspiration was suggestive of a malignant fibrous histiocytoma. After further resection, the final diagnosis was dedifferentiated chondrosarcoma. A new soft-tissue component or rapid growth of the mass can be indicative of a diagnosis of dedifferentiated chondrosarcoma.