American Journal of Neuroradiology 21:1127-1132 (6 2000)
© 2000 American Society of Neuroradiology
ARTICLE
Sonography for the Detection of Cervical Lymph Node Metastases among Patients with Tongue Cancer:Criteria for Early Detection and Assessment ofFollow-up Examination Intervals
a From the Departments of Oral and Maxillofacial Radiology (Ke.Y., T.K., Ka.Y. E.N., S.K.) and Radiology (N.K.), Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582 Japan; the Department of Radiology (S.U.), Kyushu Medical Center; and the Department of Radiology (J.O.), New Koga Hospital, Tenjin-cho 120, Kurume 830-0033, Japan
BACKGROUND AND PURPOSE: Because the presence of cervical metastasis is one of the factors influencing the outcome of patients with carcinoma of the head and neck, its early detection is potentially very important. The purpose of this study was to evaluate the characteristic changes of cervical metastasis revealed by sonography during follow-up and to assess an adequate interval for follow-up sonography of the neck among patients with tongue cancer.
METHODS: Forty-three of 44 consecutive patients with squamous cell carcinoma of the tongue, who had undergone interstitial brachytherapy, were examined with sonography of the neck during the posttherapeutic follow-up period.
RESULTS: Seventeen cervical lymph node metastases were found in 12 of 43 patients during follow-up. Of these 17 cervical metastases, 16 (94.1%) were accurately diagnosed and one (5.9%) was misdiagnosed as nonmetastatic based on sonographic findings. Sonography of the neck performed in seven patients at an interval of less than 1 month since the last follow-up imaging showed 9 (90.0%) of 10 metastases increased by up to 2 mm in short-axis diameter. Five patients who were followed up at an interval of more than 1 month since the last follow-up imaging had seven metastases increase by 3 to 8 mm in short-axis diameter or a change of echogenicity in the internal structure of lymph nodes or both. Pathologic examinations showed extranodal spread in 3 (42.9%) of these 7 metastases.
CONCLUSION: Changes both in size and internal echogenicity can occur as quickly as 2 to 4 weeks between sonographic examinations. Therefore, in high-risk patients, or in those with suspicious sonographic findings, short-interval follow-up sonographic examinations are recommended at least during the first posttherapeutic year. Our findings suggest that follow-up sonography of the neck should be performed monthly, at least during the first posttherapeutic year.