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ARTICLE

Amyloidoma of the Skull Base

William A. Simoens,a, Luc van den Hauwea, Eddy Van Hedenta, Fabienne Warsona, Roland Demaeseneera, David Williamsa and Arthur M.A. De Scheppera

a From the Departments of Radiology (W.A.S., E.V.H.), Pathology (F.W.), Internal Medicine (R.D.), and ENT (D.W.), Algemeen Stedelijk Ziekenhuis Campus Aalst, Aalst, and the Department of Radiology (W.A.S., L.v.d.H., A.M.A.D.S.), Universitair Ziekenhuis Antwerpen, University of Antwerp, Antwerp, Belgium.

Summary: We report a case of a primary amyloidoma of the skull base. Plain radiography and CT showed a lytic, highly destructive lesion with multiple scattered calcifications within. MR imaging revealed that the tumor was iso- to hypointense to muscle on T1-weighted images and extremely hypointense on T2-weighted images. In contrast to two previous reports, marked enhancement after the administration of contrast material was absent. Bone amyloidomas are very rare and are frequently misinterpreted as chondrosarcomas.




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