AJDRAJNR - American Journal of Neuroradiology

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ARTICLE

Aggressive Epithelial Odontogenic Ghost Cell Tumor in the Mandible: CT and MR Imaging Findings

Hyung-Jin Kim,a, Sung-Kyu Choia, Choong Jae Leea and Chang Hae Suha

a From the Departments of Radiology (H-J.K., S-K.C., C.H.S.) and Plastic and Reconstructive Surgery (C.J.L.), Inha University Hospital, Inchon, Korea.

Summary: We report a case of aggressive epithelial odontogenic ghost cell tumor arising from the mandible in a 32-year-old man. On CT and MR studies, the tumor was seen as a large, heterogeneous soft-tissue mass that caused marked destruction of the mandible and invaded the mouth floor and tongue base. The tumor displayed a variety of densities and signal intensities on CT and MR images, which correlated well with the degree of cellularity of epithelial islands, abundance of ghost cells and eosinophilic materials, calcification, and cystic areas on histologic sections. Owing to the unpredictable biological behavior of this type of tumor, careful, long-term follow-up is highly recommended.