American Journal of Neuroradiology 22:1860-1863 (November 2001)
© 2001 American Society of Neuroradiology
SPINE
Age of Fracture and Clinical Outcomes of Percutaneous Vertebroplasty
a From the Department of Radiology, University of Virginia Health Services, Charlottesville.
BACKGROUND AND PURPOSE: The patient populations that are most likely to benefit from percutaneous vertebroplasty (PVP) are uncertain. Our purpose was to evaluate the effect of the age of vertebral compression fracture (VCF) on clinical improvement after PVP.
METHODS: We performed a retrospective review of charts of patients who had undergone PVP for painful osteoporotic VCFs at our institution. The preprocedural and postprocedural outcome measurements of pain, mobility, and analgesic use were compared for 80 treatment sessions in 75 patients (122 total vertebrae treated). We assessed the association between the duration of pain before PVP and postprocedural outcomes by using multivariable analysis.
RESULTS: Age of fracture at time of PVP was not independently associated with postprocedural pain or activity. Increasing age of fracture was independently associated with slightly greater postprocedural analgesic requirement, at least for patients who required narcotics at baseline before PVP. Greater preprocedural analgesic requirement was independently associated with greater postprocedural analgesic requirement. Reduced preprocedural mobility was independently associated with reduced postprocedural mobility.
CONCLUSION: PVP is a highly efficacious therapy for relief of pain and improvement in mobility, regardless of fracture age. PVP also is efficacious in reducing analgesic requirement, although this effect may be slightly blunted in patients who require narcotics before the procedure and in those who have older fractures.
This article has been cited by other articles:
 |
|
 |
|
  M E Jensen, J K McGraw, J F Cardella, and J A Hirsch Position statement on percutaneous vertebral augmentation: a consensus statement developed by the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, American Association of Neurological Surgeons/Congress of Neurological Surgeons, and American Society of Spine Radiology JNIS, December 1, 2009; 1(2): 181 - 185. [Full Text] [PDF]
|
|
|
|
|
|
M E Jensen, J K McGraw, J F Cardella, and J A Hirsch Position statement on percutaneous vertebral augmentation: a consensus statement developed by the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, American Association of Neurological Surgeons/Congress of Neurological Surgeons, and American Society of Spine Radiology JNIS, October 30, 2009; (2009) j.jvir.2009.04.022v1. [Full Text] [PDF]
|
|
|
|
 |
|
 D. F. Kallmes, B. A. Comstock, P. J. Heagerty, J. A. Turner, D. J. Wilson, T. H. Diamond, R. Edwards, L. A. Gray, L. Stout, S. Owen, et al. A Randomized Trial of Vertebroplasty for Osteoporotic Spinal Fractures N. Engl. J. Med., August 6, 2009; 361(6): 569 - 579. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A J Evans, K E Kip, and S M Boutin Prospective assessment of pain and functional status after vertebroplasty for treatment of vertebral compression fractures JNIS, July 3, 2009; (2009) jnis.2009.000158v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. P. J. Muijs, M. J. Nieuwenhuijse, A. R. Van Erkel, and P. D. S. Dijkstra Percutaneous vertebroplasty for the treatment of osteoporotic vertebral compression fractures: EVALUATION AFTER 36 MONTHS J Bone Joint Surg Br, March 1, 2009; 91-B(3): 379 - 384. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M.E. Jensen, J.K. McGraw, J.F. Cardella, and J.A. Hirsch Position Statement on Percutaneous Vertebral Augmentation: A Consensus Statement Developed by the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, American Association of Neurological Surgeons/Congress of Neurological Surgeons, and American Society of Spine Radiology AJNR Am. J. Neuroradiol., September 1, 2007; 28(8): 1439 - 1443. [Full Text] [PDF]
|
|
|
|
|
|
K.F. Layton, K.R. Thielen, H.J. Cloft, and D.F. Kallmes Acute Vertebral Compression Fractures in Patients with Multiple Myeloma: Evaluation of Vertebral Body Edema Patterns on MR Imaging and the Implications for Vertebroplasty. AJNR Am. J. Neuroradiol., September 1, 2006; 27(8): 1732 - 1734. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.H.J. Voormolen, W.J. van Rooij, M. Sluzewski, Y. van der Graaf, L.E.H. Lampmann, P.N.M. Lohle, and J.R. Juttmann Pain Response in the First Trimester after Percutaneous Vertebroplasty in Patients with Osteoporotic Vertebral Compression Fractures with or without Bone Marrow Edema AJNR Am. J. Neuroradiol., August 1, 2006; 27(7): 1579 - 1585. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. K. Singh, T. K. Pilgram, and L. A. Gilula Osteoporotic Compression Fractures: Outcomes after Single- versus Multiple-Level Percutaneous Vertebroplasty Radiology, January 1, 2006; 238(1): 211 - 220. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. G. Hadjipavlou, M. N. Tzermiadianos, P. G. Katonis, and M. Szpalski Percutaneous vertebroplasty and balloon kyphoplasty for the treatment of osteoporotic vertebral compression fractures and osteolytic tumours J Bone Joint Surg Br, December 1, 2005; 87-B(12): 1595 - 1604. [Full Text] [PDF]
|
|
|
|
|
|
H. M. Do, B. S. Kim, M. L. Marcellus, L. Curtis, and M. P. Marks Prospective Analysis of Clinical Outcomes after Percutaneous Vertebroplasty for Painful Osteoporotic Vertebral Body Fractures AJNR Am. J. Neuroradiol., August 1, 2005; 26(7): 1623 - 1628. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. B. Brown, C. B. Glaiberman, L. A. Gilula, and J. S. Shimony Correlation Between Preprocedural MRI Findings and Clinical Outcomes in the Treatment of Chronic Symptomatic Vertebral Compression Fractures with Percutaneous Vertebroplasty Am. J. Roentgenol., June 1, 2005; 184(6): 1951 - 1955. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F G Irani, J P Morales, T Sabharwal, R Dourado, A Gangi, and A Adam Successful treatment of a chronic post-traumatic 5-year-old osteoporotic vertebral compression fracture by percutaneous vertebroplasty Br. J. Radiol., March 1, 2005; 78(927): 261 - 264. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. B. Brown, L. A. Gilula, M. Sehgal, and J. S. Shimony Treatment of Chronic Symptomatic Vertebral Compression Fractures with Percutaneous Vertebroplasty Am. J. Roentgenol., February 1, 2004; 182(2): 319 - 322. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. F. Kallmes and M. E. Jensen Percutaneous Vertebroplasty Radiology, October 1, 2003; 229(1): 27 - 36. [Abstract] [Full Text] [PDF]
|
|