AJDRAJNR - American Journal of Neuroradiology

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BRAIN

Intradural Primary Chondroblastic Osteosarcoma: Case Report

Matthew T. Walkera, Leon R. Toyea, Stephen W. Coonsa, Randall W. Portera and Robert C. Wallacea

a From the Division of Neuroradiology (M.T.W., R.C.W.), Department of Radiology (L.R.T.), Division of Neuropathology Research (S.W.C.), and Department of Neurosurgery (R.W.P.), Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ.

Summary: We report a rare case of intradural primary osteosarcoma (IPOS) in a 74-year-old man with aphasia and right-sided hemiparesis. Radiologic workup revealed a large, partially calcified, left-sided frontotemporal intracranial mass lesion. At surgery, the tumor was found to be entirely intradural; it involved the brain and subarachnoid space of the left sylvian fissure. The adjacent dura was uninvolved. Neuropathologic findings confirmed the diagnosis of chondroblastic osteosarcoma. To our knowledge, this is the sixth reported case of IPOS and the first reported case of the chondroblastic subtype.