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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 22:301-304 (2 2001)
© 2001 American Society of Neuroradiology

ARTICLE

Cranial MR Imaging of Sequelae of Prefrontal Lobotomy

Akira Uchino^,a, Akira Kato^a, Takefumi Yuzuriha^a, Yuki Takashima^a and Sho Kudo^a

^a From the Department of Radiology (A.U., A.K., S.K.), Saga Medical School, and the Departments of Psychiatry (T.Y.) and Neurology (Y.T.), National Hizen Hospital, Saga, Japan.

BACKGROUND AND PURPOSE: Although prefrontal lobotomy is an obsolete treatment for schizophrenia, we still encounter patients who have undergone this procedure. The purpose of this study was to describe the MR imaging findings of sequelae of prefrontal lobotomy.

METHODS: We retrospectively reviewed cranial MR images of eight patients with schizophrenia who underwent prefrontal lobotomy approximately 50 years previously.

RESULTS: In all patients, a bilateral cavitary lesion with a thick wall was found in the frontal white matter. The genu of the corpus callosum was mildly to markedly atrophic. The size and location of the cavity and the degree of callosal atrophy were correlated.

CONCLUSION: MR imaging is useful for the diagnosis of sequelae of prefrontal lobotomy, including cavitary lesions with dense walls of gliosis and secondary degeneration of the genu of the corpus callosum.