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ARTICLE

Sonographic, CT, and MR Imaging Findings in Diffuse Infiltrative Retinoblastoma: Report of Two Cases with Histologic Comparison

Hervé J. Brisse,a, Livia Lumbrosoa, Paul C. Fréneauxa, Pierre Validirea, François P. Doza, Erica J. Quintanaa, Olivier Bergesa, Laurence C. Desjardinsa and Sylvia G. Neuenschwandera

a From the Departments of Radiology (H.J.B., S.G.N.), Ophthalmology (L.L., L.C.D.), Pathology (P.C.F.), and Pediatric Oncology (F.P.D., E.J.Q.), Institut Curie, Paris, France; the Department of Pathology, Institut Mutualiste Montsouris, Paris, France (P.V.); and the Department of Radiology, Fondation Ophtalmologique A. de Rothschild, Paris, France (O.B.).

Summary: Diffuse infiltrating retinoblastoma is a rare form of retinoblastoma. We report two cases of this disease in which sonographic, CT, and MR imaging findings were compared with histologic studies obtained after enucleation. Although nonspecific, MR imaging provides valuable morphologic data for the diagnosis of diffuse infiltrating retinoblastoma and may help in decisions regarding enucleation.




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