Advanced

AJNR - American Journal of Neuroradiology

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Campi, A. Articles by Scotti, G. Search for Related Content PubMed PubMed Citation Articles by Campi, A. Articles by Scotti, G.

American Journal of Neuroradiology 22:577-582 (3 2001)
© 2001 American Society of Neuroradiology

ARTICLE

Spinal Cord Involvement in Primary Angiitis of the Central Nervous System: A Report of Two Cases

Adriana Campi^,a, G. Benndorf^a, V. Martinelli^a, M. R. Terreni^a and G. Scotti^a

^a From the Departments of Neuroradiology (A.C., G.S.), Neurology (V.M.), and Pathology (M.R.T.), Scientific Institute and University San Raffaele, Milan, Italy; and the Department of Radiology, Charité, Humboldt University Berlin, Germany (G.B.).

Summary: We report two patients with suspected primary angiitis of the CNS who underwent serial contrast-enhanced MR imaging of the spinal cord. MR abnormalities were multiple and enhancing, and located within the cervical and thoracic cord. Brain MR findings and brain biopsy specimens were positive for primary angiitis of the CNS. On follow-up MR studies, obtained after steroid and immunosuppressive therapy, a significant decrease in the number and size of the enhancing and nonenhancing abnormalities was observed, along with clinical improvement. Numerous small and enhancing abnormalities with a primarily posterior location, seen at the onset of the disease and resolved on follow-up studies, may be considered suggestive of a diagnosis of primary angiitis of the CNS.

This article has been cited by other articles:

				R. Manara, F. Schiavon, V. Carraro, A. Cagnin, and C. Briani Angiographic Diagnosis of Primary Central Nervous System Vasculitis With Spinal Cord Involvement Arch Neurol, April 1, 2009; 66(4): 532 - 533. [Full Text] [PDF]

				C. Salvarani, R. D. Brown Jr, K. T. Calamia, T.J.H. Christianson, J. Huston III, J. F. Meschia, C. Giannini, D. V. Miller, and G. G. Hunder Primary CNS vasculitis with spinal cord involvement Neurology, June 10, 2008; 70(24_Part_2): 2394 - 2400. [Abstract] [Full Text] [PDF]