AJDRAJNR - American Journal of Neuroradiology

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Inglese, M.
Right arrow Articles by Filippi, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Inglese, M.
Right arrow Articles by Filippi, M.

American Journal of Neuroradiology 22:681-684 (4 2001)
© 2001 American Society of Neuroradiology

ARTICLE

Scan-Rescan Variation of Measures Derived from Brain Magnetization Transfer Ratio Histograms Obtained in Healthy Volunteers by Use of a Semi-interleaved Magnetization Transfer Sequence

Matilde Inglesea, Mark A. Horsfielda and Massimo Filippi,a

a From the Neuroimaging Research Unit, Department of Neuroscience, Scientific Institute Ospedale San Raffaele, Milan, Italy (M.I., M.F.), and the Division of Medical Physics, University of Leicester, Leicester, UK (M.A.H.).

Summary: A novel semiinterleaved gradient-echo (GE) sequence for quantitative measurement of magnetization transfer ratio (MTR) is described. With this sequence, several lines of k-space are collected for the non-MT image then several lines are collected for the MT image, thus building up the entire k-space in distinct acquisition blocks, with a good trade-off between motion-induced misregistration and degree of MT effect. The scan-rescan coefficients of variation for several MTR histogram-derived measures from 10 healthy volunteers scanned serially with this semiinterleaved sequence proved to be lower than those achieved using a conventional GE sequence. This sequence may be useful in a clinical environment to measure MTR changes over time more reliably than when acquiring the non-MT and MT images sequentially, which inevitably are affected by patient motion.




This article has been cited by other articles:


Home page
 Arch NeurolHome page
M. Filippi, M. A. Rocca, E. Pagani, G. Iannucci, M. P. Sormani, F. Fazekas, S. Ropele, O. R. Hommes, and G. Comi
European Study on Intravenous Immunoglobulin in Multiple Sclerosis: Results of Magnetization Transfer Magnetic Resonance Imaging Analysis
Arch Neurol, September 1, 2004; 61(9): 1409 - 1412.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
M. Inglese, J.H.T.M. van Waesberghe, M. Rovaris, K. Beckmann, F. Barkhof, D. Hahn, L. Kappos, D.H. Miller, C. Polman, C. Pozzilli, et al.
The effect of interferon {beta}-1b on quantities derived from MT MRI in secondary progressive MS
Neurology, March 11, 2003; 60(5): 853 - 860.
[Abstract] [Full Text] [PDF]


Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X