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ARTICLE

Tumefactive Fibroinflammatory Lesion of the Neck with Progressive Invasion of the Meninges, Skull Base, Orbit, and Brain

Andrei I. Holodnya, Claudia F. Kirscha, Meera Hameeda and Gary Sclar,a

a From the Departments of Radiology (A.I.H., C.F.K), Pathology (M.H.), and Neurosciences (G.S.), New Jersey Medical School, Newark, NJ.

Summary: Tumefactive fibroinflammatory lesions of the head and neck are rare. CNS involvement has not been reported. We present a histologically proven case of a tumefactive fibroinflammatory lesion that originated in the left side of the neck and progressed over 2 years to involve the meninges, the cavernous sinuses, the right temporal lobe, and the right orbit. The lesion caused destruction of the skull base and a subdural hematoma. The relationship of the present lesion to idiopathic hypertrophic pachymeningitis and Tolosa-Hunt syndrome is discussed.




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