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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 22:1357-1361 (8 2001)
© 2001 American Society of Neuroradiology

ARTICLE

Persistence of Gadolinium in CSF: A Diagnostic Pitfall in Patients with End-stage Renal Disease

Ansaar T. Rai^a and Jeffery P. Hogg^a

^a From the Department of Radiology, West Virginia University, 2278 HSCS, Morgantown, WV 26506–9235.

Summary: Two dialysis-dependent patients with end-stage renal disease underwent brain and spine MR imaging a few days after having undergone gadolinium-enhanced imaging studies. Increased signal intensity in the subarachnoid space on T1-weighted and fluid-attenuated inversion recovery images was noted. Excretion of gadolinium into the CSF was proven in one case by mass spectrometry. Dialysis-dependent patients with end-stage renal disease and neurologic abnormalities often undergo contrast-enhanced MR imaging. Recognition that these patients may show increased signal intensity in the subarachnoid space because of gadolinium excretion into CSF may prevent diagnostic errors.

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