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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 23:1686-1691, November-December 2002
© 2002 American Society of Neuroradiology

Case Report
PEDIATRICS

Advanced MR Imaging of Cortical Dysplasia with or without Neoplasm: A Report of Two Cases

Jay J. Pillai^a, Richard B. Hessler^b, Jerry D. Allison^a, Yong D. Park^c, Mark R. Lee^d and Tom Lavin^a

^a Department of Radiology, the Medical College of Georgia, Augusta, GA
^b Department of Pathology, the Medical College of Georgia, Augusta, GA
^c Department of Neurology, the Medical College of Georgia, Augusta, GA
^d Department of Neurosurgery, the Medical College of Georgia, Augusta, GA

Address reprint requests to Jay J. Pillai, MD, Division of Neuroradiology, Department of Radiology, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912

Summary: We herein describe two cases of patients with epilepsy with occipital lobe cortical dysplasia who were studied with both MR spectroscopy and MR diffusion imaging in addition to conventional MR imaging. Greater diffusion abnormalities, as well as more marked decreases in N-acetylaspartate, were observed to occur in the patient harboring a low grade neoplasm within an area of cortical dysplasia than in the patient with cortical dysplasia alone.