American Journal of Neuroradiology 23:213-219, February 2002
© 2002 American Society of Neuroradiology
BRAIN
Contrast-Enhanced 3D MR Angiography of the Carotid Artery: Comparison with Conventional Digital Subtraction Angiography
a Department of Neuroradiology, University of Bern, Switzerland
b Department of Neurosurgery, University of Bern, Switzerland
c Department of Neurology, University of Bern, Switzerland
Address reprint requests to Luca Remonda, MD, University of Bern, Inselspital, Department of Neuroradiology, Freiburgstrasse 10, CH-3010 Bern, Switzerland
BACKGROUND AND PURPOSE: Since 1996, several preliminary studies have shown the usefulness of contrast material–enhanced MR angiography for imaging supraaortic vessels. The aim of this study was to compare the accuracy of contrast-enhanced 3D MR angiography with that of digital subtraction angiography (DSA) in the evaluation of carotid artery stenosis.
METHODS: A blinded comparison of first-pass contrast-enhanced MR angiography with conventional DSA was performed in 120 patients (240 arteries). MR angiography was performed with a 1.5-T magnet with gradient overdrive equipment, by using a coronal radiofrequency-spoiled 3D fast low-angle–shot sequence after the intravenous injection of gadodiamide. The guidelines of the North American Symptomatic Carotid Endarterectomy Trial for measuring stenosis of the internal carotid artery were applied on maximum intensity projection (MIP) images and conventional catheter angiograms.
RESULTS: Grading of stenoses on MR angiograms agreed with grading of stenoses on DSA images in 89% of arteries. In the severe stenosis group (70–99%), agreement was 93%. All internal carotid occlusions (n = 28) and seven of nine pseudo-occlusions were accurately detected with contrast-enhanced MR angiography. The correlation between MR angiography and DSA for determination of minimal, moderate, and severe stenoses and occlusion was statistically significant (r = 0.91, P< .001).
CONCLUSIONS: This investigation with a large number of patients confirms that contrast-enhanced MR angiography could become a diagnostic alternative to DSA in the treatment of patients with carotid artery disease.
This article has been cited by other articles:
 |
|
 |
|
  L.S. Babiarz, J.M. Romero, E.K. Murphy, B. Brobeck, P.W. Schaefer, R.G. Gonzalez, and M.H. Lev Contrast-Enhanced MR Angiography Is Not More Accurate Than Unenhanced 2D Time-of-Flight MR Angiography for Determining >=70% Internal Carotid Artery Stenosis AJNR Am. J. Neuroradiol., April 1, 2009; 30(4): 761 - 768. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Tomasian, N. Salamon, D. G. Lohan, M. Jalili, J. P. Villablanca, and J. P. Finn Supraaortic Arteries: Contrast Material Dose Reduction at 3.0-T High-Spatial-Resolution MR Angiography--Feasibility Study Radiology, December 1, 2008; 249(3): 980 - 990. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R.P. Lim, M. Shapiro, E.Y. Wang, M. Law, J.S. Babb, L.E. Rueff, J.S. Jacob, S. Kim, R.H. Carson, T.P. Mulholland, et al. 3D Time-Resolved MR Angiography (MRA) of the Carotid Arteries with Time-Resolved Imaging with Stochastic Trajectories: Comparison with 3D Contrast-Enhanced Bolus-Chase MRA and 3D Time-Of-Flight MRA AJNR Am. J. Neuroradiol., November 1, 2008; 29(10): 1847 - 1854. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. M. Debrey, H. Yu, J. K. Lynch, K.-O. Lovblad, V. L. Wright, S.-J. D. Janket, and A. E. Baird Diagnostic Accuracy of Magnetic Resonance Angiography for Internal Carotid Artery Disease: A Systematic Review and Meta-Analysis Stroke, August 1, 2008; 39(8): 2237 - 2248. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. R. Bates, C. J. D. Babb, D. E. Casey, C. U. Cates, G. R. Duckwiler, T. E. Feldman, W. A. Gray, K. Ouriel, E. D. Peterson, K. Rosenfield, et al. ACCF/SCAI/SVMB/SIR/ASITN 2007 Clinical Expert Consensus Document on Carotid Stenting: A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents (ACCF/SCAI/SVMB/SIR/ASITN Clinical Expert Consensus Document Committee on Carotid Stenting) Vascular Medicine, February 1, 2007; 12(1): 35 - 83. [PDF]
|
|
|
|
|
|
K. Nael, J. P. Villablanca, W. B. Pope, T. O. McNamara, G. Laub, and J. P. Finn Supraaortic Arteries: Contrast-enhanced MR Angiography at 3.0 T--Highly Accelerated Parallel Acquisition for Improved Spatial Resolution over an Extended Field of View Radiology, February 1, 2007; 242(2): 600 - 609. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. S. Bartlett, T. D. Walters, S. P. Symons, and A. J. Fox Carotid Stenosis Index Revisited With Direct CT Angiography Measurement of Carotid Arteries to Quantify Carotid Stenosis Stroke, February 1, 2007; 38(2): 286 - 291. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 American Society of Interventional & Therapeutic N, Society for Cardiovascular Angiography and Interve, Society for Vascular Medicine and Biology, Society of Interventional Radiology, E. R. Bates, J. D. Babb, D. E. Casey Jr, C. U. Cates, G. R. Duckwiler, T. E. Feldman, et al. ACCF/SCAI/SVMB/SIR/ASITN 2007 Clinical Expert Consensus Document on Carotid Stenting: A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents (ACCF/SCAI/SVMB/SIR/ASITN Clinical Expert Consensus Document Committee on Carotid Stenting) J. Am. Coll. Cardiol., January 2, 2007; 49(1): 126 - 170. [Full Text] [PDF]
|
|
|
|
|
|
E.S. Bartlett, S.P. Symons, and A.J. Fox Correlation of Carotid Stenosis Diameter and Cross-Sectional Areas with CT Angiography AJNR Am. J. Neuroradiol., March 1, 2006; 27(3): 638 - 642. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D Mitra, D Connolly, S Jenkins, P English, D Birchall, C Mandel, K Shrikanth, B Gregson, and A Gholkar Comparison of image quality, diagnostic confidence and interobserver variability in contrast enhanced MR angiography and 2D time of flight angiography in evaluation of carotid stenosis. Br. J. Radiol., March 1, 2006; 79(939): 201 - 207. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E.S. Bartlett, T.D. Walters, S.P. Symons, and A.J. Fox Quantification of Carotid Stenosis on CT Angiography AJNR Am. J. Neuroradiol., January 1, 2006; 27(1): 13 - 19. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. W. Yang, J. C. Carr, S. F. Futterer, M. D. Morasch, B. P. Yang, S. M. Shors, and J. P. Finn Contrast-Enhanced MR Angiography of the Carotid and Vertebrobasilar Circulations AJNR Am. J. Neuroradiol., September 1, 2005; 26(8): 2095 - 2101. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. L. Wright, W. Olan, B. Dick, H. Yu, N. Alberts-Grill, L. L. Latour, and A. E. Baird Assessment of CE-MRA for the rapid detection of supra-aortic vascular disease Neurology, July 12, 2005; 65(1): 27 - 32. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Anzalone, F. Scomazzoni, R. Castellano, L. Strada, C. Righi, L. S. Politi, M. A. Kirchin, R. Chiesa, and G. Scotti Carotid Artery Stenosis: Intraindividual Correlations of 3D Time-of-Flight MR Angiography, Contrast-enhanced MR Angiography, Conventional DSA, and Rotational Angiography for Detection and Grading Radiology, July 1, 2005; 236(1): 204 - 213. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Berg, Z. Zhang, A. Ikonen, P. Sipola, R. Kalviainen, H. Manninen, and R. Vanninen Multi-Detector Row CT Angiography in the Assessment of Carotid Artery Disease in Symptomatic Patients: Comparison with Rotational Angiography and Digital Subtraction Angiography AJNR Am. J. Neuroradiol., May 1, 2005; 26(5): 1022 - 1034. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-Y. Gauvrit, X. Leclerc, M. Pernodet, B. Lubicz, J.-P. Lejeune, D. Leys, and J.-P. Pruvo Intracranial Aneurysms Treated with Guglielmi Detachable Coils: Usefulness of 6-Month Imaging Follow-Up with Contrast-Enhanced MR Angiography AJNR Am. J. Neuroradiol., March 1, 2005; 26(3): 515 - 521. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. C. Wang, D. Saloner, and J. H. Rapp Characteristics of Carotid Plaque as Risk Factors for Stroke Perspectives in Vascular Surgery and Endovascular Therapy, September 1, 2004; 16(3): 193 - 199. [Abstract] [PDF]
|
|
|
|
 |
|
 J. K. DeMarco, J. Huston III, and M. A. Bernstein Evaluation of Classic 2D Time-of-Flight MR Angiography in the Depiction of Severe Carotid Stenosis Am. J. Roentgenol., September 1, 2004; 183(3): 787 - 793. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. K.S. U-King-Im, R. A. Trivedi, J. J. Cross, N. J.P. Higgins, W. Hollingworth, M. Graves, I. Joubert, P. J. Kirkpatrick, N. M. Antoun, and J. H. Gillard Measuring Carotid Stenosis on Contrast-Enhanced Magnetic Resonance Angiography: Diagnostic Performance and Reproducibility of 3 Different Methods Stroke, September 1, 2004; 35(9): 2083 - 2088. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. H. Wierks and N. Labropoulos Noninvasive Carotid Imaging Perspectives in Vascular Surgery and Endovascular Therapy, June 1, 2004; 16(2): 89 - 99. [Abstract] [PDF]
|
|
|
|
|
|
J. M. U-King-Im, R. A. Trivedi, M. J. Graves, N. J. Higgins, J. J. Cross, B. D. Tom, W. Hollingworth, H. Eales, E. A. Warburton, P. J. Kirkpatrick, et al. Contrast-enhanced MR angiography for carotid disease: Diagnostic and potential clinical impact Neurology, April 27, 2004; 62(8): 1282 - 1290. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. J. Nederkoorn, O. E. H. Elgersma, Y. van der Graaf, B. C. Eikelboom, L. J. Kappelle, and W. P. T. M. Mali Carotid Artery Stenosis: Accuracy of Contrast-enhanced MR Angiography for Diagnosis Radiology, September 1, 2003; 228(3): 677 - 682. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Borisch, M. Horn, B. Butz, N. Zorger, B. Draganski, T. Hoelscher, U. Bogdahn, and J. Link Preoperative Evaluation of Carotid Artery Stenosis: Comparison of Contrast-Enhanced MR Angiography and Duplex Sonography with Digital Subtraction Angiography AJNR Am. J. Neuroradiol., June 1, 2003; 24(6): 1117 - 1122. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Alvarez-Linera, J. Benito-Leon, J. Escribano, J. Campollo, and R. Gesto Prospective Evaluation of Carotid Artery Stenosis: Elliptic Centric Contrast-Enhanced MR Angiography and Spiral CT Angiography Compared with Digital Subtraction Angiography AJNR Am. J. Neuroradiol., May 1, 2003; 24(5): 1012 - 1019. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. U-King-Im, R. Trivedi, J. H. Gillard, D. C.C. Johnston, J. D. Eastwood, and L. B. Goldstein Contrast-Enhanced Magnetic Resonance Angiography Carotid Arteries * Response Stroke, May 1, 2003; 34 (5): e15 - e15. [Full Text] [PDF]
|
|
|
|
|
|
A. Barth and C. Bassetti Patient Selection for Carotid Endarterectomy: How Far Is Risk Modeling Applicable to the Individual? Stroke, February 1, 2003; 34(2): 524 - 527. [Abstract] [Full Text] [PDF]
|
|