American Journal of Neuroradiology 23:447-451, March 2002
© 2002 American Society of Neuroradiology
Case Report
INTERVENTIONAL
Intraarterially Administered Abciximab as an Adjuvant Thrombolytic Therapy: Report of Three Cases
a Neurovascular Center, Inje University, Seoul Paik Hospital, Seoul, Korea
b Departments of Radiology Seoul National University College of Medicine, Clinical Research Institute, Seoul, Korea
c Departments of Neurosurgery, Seoul National University College of Medicine, Clinical Research Institute, Seoul, Korea
d Seoul National University Hospital, Seoul, Korea
Address reprint requests to Moon Hee Han, MD, Department of Diagnostic Radiology, Seoul National University Hospital, 28 Yongon-dong, Chongno-ku, Seoul 110–744, Korea
Summary: The intravenous administration of abciximab can be used as an adjuvant therapy to facilitate thrombolysis for acute cerebrovascular occlusion. However, to our knowledge, the intraaterial administration of abciximab has not been reported. We recently treated three patients with acute thrombosis of the cerebral arteries by using an intraarterial infusion of urokinase and abciximab. Even with small doses, we achieved rapid and complete recanalization without complications. We believe that the intraarterial infusion of abciximab may be promising for effective and safe recanalization of acute thrombotic occlusion of cerebral arteries.
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