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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 23:706-710, April 2002
© 2002 American Society of Neuroradiology

INTERVENTIONAL

Study of the Patency of Small Arterial Branches after Stent Placement with an Experimental in Vivo Model

Osamu Masuo^a, Tomoaki Terada^a, Gary Walker^b, Mitsuharu Tsuura^a, Hiroyuki Matsumoto^a, Kazuo Tohya^c, Michio Kimura^c, Kunio Nakai^a and Toru Itakura^a

^a Department of Neurological Surgery, Kansai College of Oriental Medicine, Osaka, Japan
^b Wakayama Medical College, the Guidant Corporation, CA, Kansai College of Oriental Medicine, Osaka, Japan
^c Department of Anatomy, Kansai College of Oriental Medicine, Osaka, Japan

Address reprint requests to Osamu Masuo, MD, Department of Neurological Surgery, Wakayama Medical College, 811–1 Kimiidera, Wakayama, 640-0012, Japan

BACKGROUND AND PURPOSE: The patency of intracranial perforating arteries after stent placement is unknown despite the general clinical use of intracranial arterial stenting.

METHODS: We deployed stainless steel stents in the abdominal aorta across the lumbar artery in eight normal rabbits in which the diameters of the abdominal arterial vessels were similar to those of human intracranial arteries. We evaluated the patency via angiographic and scanning electron microscopic methods 3 months after stent placement. Histopathologic evaluation was also performed for one rabbit.

RESULTS: The lumbar arteries were patent, even when stent struts crossed the ostium, except in one rabbit in which intimal dissection occurred intraoperatively. The scanning electron microscopy showed that the regenerative endothelium had grown onto the strut at the ostium of the lumbar artery.

CONCLUSION: We confirmed the patency of the lumbar arteries in this study by using normal rabbits. Thus, intracranial stenting may not pose a risk of occluding perforating arteries of the same diameter of the lumbar artery, even if stent struts cover the ostium.

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