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Technical Note
BRAIN

Visualization of Microvascularity in Glioblastoma Multiforme With 8-T High-Spatial-Resolution MR Imaging

Gregory A. Christoforidisa, John C. Greculaa, Herbert B. Newtonb, Allahyar Kangarlua, Amir M. Abduljalila, Petra Schmalbrocka and Donald W Chakeresa

a Department of Radiology, the Ohio State University Medical Center, Columbus
b Department of Neurology, the Ohio State University Medical Center, Columbus

Address reprint requests to Gregory A. Christoforidis, M.D., Assistant Professor, Department of Radiology, the Ohio State University Medical Center, 168 Means Hall, 1654 Upham Drive, Columbus, OH 43221

Summary: We used 8-T high-spatial-resolution gradient-echo MR imaging to directly visualize microvascularity in pathologically proved glioblastoma multiforme. Images were compared with 1.5-T high-spatial-resolution fast spin-echo T2-weighted images and digital subtraction angiograms. Preliminary data indicate that 8-T high-spatial-resolution MR imaging may enable the identification of areas of abnormal microvascularity in glioblastoma multiforme that are not visible with other routine clinical techniques.




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