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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 23:1564-1567, October 2002
© 2002 American Society of Neuroradiology

Case Report
BRAIN

Medulloblastoma with Extensive Nodularity: Single Photon Emission CT Study with Iodine-123 Metaiodobenzylguanidine

Yuichiro Naitoh^a, Toshio Sasajima^a, Hiroyuki Kinouchi^a, Shigeki Mikawa^a and Kazuo Mizoi^a

^a From the Department of Neurosurgery, Akita University School of Medicine, Akita, Japan

Address reprint requests to Toshio Sasajima, MD, PhD, Department of Neurosurgery, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan

Summary: We present the case of an infant with medulloblastoma with extensive nodularity, which had been called cerebellar neuroblastoma. MR imaging clearly revealed a nodular enhancement, which appeared as a grape-like lesion. Single photon emission CT revealed markedly high iodine-123 metaiodobenzylguanidine uptake in the enhancing tumor. Iodine-123 metaiodobenzylguanidine single photon emission CT may be useful in the diagnosis of medulloblastoma with extensive nodularity, which has been considered to be a subgroup of medulloblastoma with extensive neuronal differentiation.

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