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American Journal of Neuroradiology 24:507-511, March 2003
© 2003 American Society of Neuroradiology

BRAIN

MR Imaging of Autopsy-Proved Paraneoplastic Limbic Encephalitis in Non-Hodgkin Lymphoma

Christina Thuerl^a, Klaus Müller^b, Jörg Laubenberger^a, Benedikt Volk^b and Mathias Langer^a

^a Departments of Radiology, University of Freiburg, Freiburg, Germany
^b Neuropathology, University of Freiburg, Freiburg, Germany

Address reprint requests to Christina Thuerl, Department of Radiology, University of Freiburg, Hugstetter Str. 55, D-79106 Freiburg, Germany

Summary: We report the case of a 26-year-old man with precursor T-cell acute lymphoblastic leukemia who developed paraneoplastic limbic encephalitis that was diagnosed on the basis of MR imaging findings and was proved post mortem. In our MR imaging studies, fluid-attenuated inversion recovery images and diffusion-weighted echo-planar images clearly depicted bilateral involvement of the medial temporal lobes and multifocal involvement of the brain, whereas T2-weighted turbo spin-echo images failed to show the changes.

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