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Technical Note
BRAIN

Safety and Feasibility of a CT Protocol for Acute Stroke: Combined CT, CT Angiography, and CT Perfusion Imaging in 53 Consecutive Patients

Wade S. Smitha, Heidi C. Roberts, Nathaniel A. Chuangb, Kenneth C. Ongb, Theodore J. Leeb, S. Claiborne Johnstona and William P. Dillonb

a Department of Neurology, University of California, San Francisco
b Department of Radiology, University of California, San Francisco

Address reprint requests to Wade Smith, MD, Department of Neurology, UCSF, 505 Parnassus Avenue, San Francisco, CA 94143

Summary: By combining non-contrast-enhanced CT imaging, CT perfusion imaging, and cranial-to-chest CT angiography (CTA), the entire cerebrovascular axis can be imaged during acute stroke. To our knowledge, the safety and feasibility of this technique have not been previously reported. In a consecutive series of 53 patients with suspected acute stroke, renal failure was not observed. Median imaging time was 27 minutes (range, 9–67 minutes). Image quality was degraded by motion in 1.3% of vessels studied. Dynamic CT perfusion data were successfully obtained in 52 patients (98% of patients). High-speed, multisection, helical CT scanners allow rapid, safe imaging of the entire neurovascular axis in patients with acute stroke by use of combined CT imaging, CT perfusion imaging, and CTA.




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