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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 24:942-945, May 2003
© 2003 American Society of Neuroradiology

Case Report
BRAIN

Unusual MR Spectroscopic Imaging Pattern of an Astrocytoma: Lack of Elevated Choline and High myo-Inositol and Glycine Levels

Ana Londoño^a, Mauricio Castillo^a, Diane Armao^a, Lester Kwock^a and Kinuko Suzuki^a

^a From the University of North Carolina School of Medicine, Chapel Hill, NC

Address reprint requests to M. Castillo, Campus Box 7510, University of North Carolina-Chapel Hill, Chapel Hill, NC 27599

Summary: We present the case of a patient with an MR imaging study showing an ill-defined intra-axial mass in the right insula and frontal lobe. The mass showed high signal intensity on T2-weighted and fluid-attenuated inversion recovery images and an unusual proton MR spectroscopic imaging pattern characterized by the presence of high levels of myo-inositol/glycine, no significant elevation of choline, and mildly reduced N-acetylaspartate. The histopathologic diagnosis was of diffuse astrocytoma with oligodendroglial components (World Health Organization grade II).

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