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American Journal of Neuroradiology 24:942-945, May 2003
© 2003 American Society of Neuroradiology

Case Report
BRAIN

Unusual MR Spectroscopic Imaging Pattern of an Astrocytoma: Lack of Elevated Choline and High myo-Inositol and Glycine Levels

Ana Londoñoa, Mauricio Castilloa, Diane Armaoa, Lester Kwocka and Kinuko Suzukia

a From the University of North Carolina School of Medicine, Chapel Hill, NC

Address reprint requests to M. Castillo, Campus Box 7510, University of North Carolina-Chapel Hill, Chapel Hill, NC 27599

Summary: We present the case of a patient with an MR imaging study showing an ill-defined intra-axial mass in the right insula and frontal lobe. The mass showed high signal intensity on T2-weighted and fluid-attenuated inversion recovery images and an unusual proton MR spectroscopic imaging pattern characterized by the presence of high levels of myo-inositol/glycine, no significant elevation of choline, and mildly reduced N-acetylaspartate. The histopathologic diagnosis was of diffuse astrocytoma with oligodendroglial components (World Health Organization grade II).






Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X