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American Journal of Neuroradiology 24:952-955, May 2003
© 2003 American Society of Neuroradiology

Case Report
BRAIN

Proton MR Spectroscopy in Wernicke Encephalopathy

Carlos A. Rugiloa,c, Marcela C. Uribe Rocad, Maria C. Zurrua, Arístides A. Capizzanoc, Gustavo A. Pontellob and Emilia M. Gattoa,d

a the Servicio de Neurología, Buenos Aires
b Sanatorio Mitre, the Servicio de Clínica Médica, Buenos Aires
c Fundación Femien, Buenos Aires
d the Programa de Parkinson y Movimientos Anormales, Hospital de Clínicas, Buenos Aires, Argentina

Address reprint requests to Emilia Mabel Gatto, MD, Juramento 1155, 3° A, Buenos Aires, Argentina, C1428DMK

Summary: Wernicke encephalopathy is caused by thiamine deficiency. Although the clinical picture has been well established for some time, clinical diagnosis is attained in only 20% of the cases. MR imaging techniques contribute to early diagnosis of Wernicke encephalopathy. We herein report MR imaging and proton MR spectroscopic findings for a patient with clinical and biochemical features consistent with Wernicke encephalopathy. Increased lactate and typical MR imaging findings are discussed in the context of the known pathophysiology of Wernicke encephalopathy.




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