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American Journal of Neuroradiology 24:1164-1166, June-July 2003
© 2003 American Society of Neuroradiology

Case Report
HEAD AND NECK

Teflon-Induced Granuloma: A False-Positive Finding with PET Resolved with Combined PET and CT

Rita A Yeretsiana, Todd M. Blodgetta, Barton F Branstetter IVa,b, Michelle M Robertsc and Carolyn C. Meltzera,d,e

a Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA
b Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA
c Department of Endocrinology, University of Pittsburgh Medical Center, Pittsburgh, PA
d Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA
e Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, PA

Address reprint requests to Carolyn Cidis Meltzer, M.D., University of Pittsburgh Medical Center, PET Facility, B-938, 200 Lothrop Street, Pittsburgh, PA

Summary: Patients who have undergone thyroidectomy may have recurrent laryngeal nerve injury; until recently, Teflon injection was commonly used for vocal cord medialization. We present a case of a patient who underwent thyroidectomy who had significantly increased and unilateral 18F-fluorodeoxyglucose uptake in the neck, which was found to be localized to the left vocal cord by use of combined positron emission tomography (PET) and CT, presumably because of a Teflon-induced granuloma. Knowledge of this potential source of false-positive PET interpretation because of its inability to precisely localize neoplastic lesions, and the use of combined PET and CT imaging, may allow precise diagnosis and prevention of unnecessary interventions.






Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X