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American Journal of Neuroradiology 24:1234-1236, June-July 2003
© 2003 American Society of Neuroradiology

Technical Note
INTERVENTIONAL

Successful Treatment of Cerebral Vasospasm by Use of Transdermal Nitroglycerin Ointment (Nitropaste)

Walter S. Lesleya, Al Lazob, John C. Chaloupkac and John B. Weigelec

a Departments of Radiology and Surgery, Saint Louis University, St. Louis, MO
b Department of Radiology, Wayne State University, Detroit, MI
c Department of Radiology, University of Iowa, Iowa City, IA

Address correspondence to Walter S. Lesley, M.D., Saint Louis University, Departments of Radiology and Surgery, Section of Neurointerventional Radiology, 3635 Vista Avenue, St. Louis, MO 63110

Summary: To our knowledge, the use of transdermal nitroglycerin ointment (Nitropaste) in the setting of intracranial vasospasm has not been described in the peer-reviewed literature. Five patients with intracranial vasospasm induced by subarachnoid hemorrhage were evaluated angiographically both before and after application of Nitropaste. All cases exhibited mild to moderate improvement in the degree of vasospasm. We conclude that Nitropaste is a simple noninvasive technique to reduce intracranial vasospasm.




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