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BRAIN

MR Findings in Murray Valley Encephalitis

Lloyd Einsiedela, Evelyn Katb, Janakan Ravindranc, John Slavotinekb and David L. Gordona

a Department of Microbiology and Infectious Diseases, Flinders Medical Centre, Adelaide, Australia
b Department of Medical Imaging, Flinders Medical Centre, Adelaide, Australia
c Department of Neurology, Flinders Medical Centre, Adelaide, Australia

Address correspondence to Dr. David L. Gordon, Department of Microbiology and Infectious Diseases, Flinders Medical Centre, Bedfork Park, South Australia, 5042, Australia

Summary: Murray Valley encephalitis (MVE) is caused by a flavivirus related to West Nile and St. Louis encephalitis viruses. We report a case of MVE resulting in quadriplegia and respiratory failure. MR imaging demonstrated thalamic hyperintensity on T2-weighted images, with similar involvement of the red nucleus, substantia nigra, and cervical cord. These findings preceded serologic diagnosis and are similar to those of Japanese encephalitis. In the appropriate setting, thalamic T2 hyperintensity is suggestive of flavivirus infection.