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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 24:1811-1813, October 2003
© 2003 American Society of Neuroradiology

Case Report
INTERVENTIONAL

De Novo Aneurysm Formation 6 and 22 Months after Initial Presentation in Two Patients

Rick Obray^a,c, Richard Clatterbuck^b,c, Alessandro Olvi^b,c, Rafael Tamargo^b,c, Kieran J. Murphy^a,c and Philippe Gailloud^a,c

^a Division of Interventional Neuroradiology, Johns Hopkins Hospital, Baltimore, MD 21287
^b Department of Radiology and Radiological Sciences, and Cerebrovascular Surgery, Johns Hopkins Hospital, Baltimore, MD 21287
^C Department of Neurological Surgery, Johns Hopkins Hospital, Baltimore, MD 21287

Address correspondence to Dr. Philippe Gailloud, Division of Interventional Neuroradiology, Department of Radiology and Radiological Sciences, Johns Hopkins Medical Institutions, Baltimore, MD 21287

Summary: Two cases of angiographically and surgically documented de novo intracranial aneurysm formation are reported. The first patient, a 32-year-old woman, developed two new aneurysms within a 6-month period, and the second patient, a 27-year-old woman, developed two new aneurysms within a 22-month period. In both patients, the new aneurysms were symptomatic, causing stroke and subarachnoid hemorrhage, respectively. The development of aneurysms de novo over such a short period of time has important implications for periodic imaging in patients considered to be at high risk for intracranial aneurysm formation.