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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 25:138-141, January 2004
© 2004 American Society of Neuroradiology

Case Report
BRAIN

Diffuse Leptomeningeal Hyperintensity on Fluid-Attenuated Inversion Recovery MR Images in Neurocutaneous Melanosis

Masato Hayashi^a, Masayuki Maeda^a, Tomoaki Maji^b, Toshio Matsubara^c, Hirokazu Tsukahara^d and Kan Takeda^a

^a Department of Radiology, Mie University School of Medicine, Mie, Japan
^b Department of Pediatrics, Mie University School of Medicine, Mie, Japan
^c Department of Neurosurgery, Mie University School of Medicine, Mie, Japan
^d Department of Pediatrics, Fukui Medical University, Fukui, Japan

Address correspondence to Dr. Masayuki Maeda, Department of Radiology, Mie University School of Medicine, 2–174 Edobashi, Tsu, Mie 514-8507, Japan

Summary: Neurocutaneous melanosis (NCM) is a rare neuroectodermal dysplasia characterized by large or multiple cutaneous congenital pigmented nevi and benign or malignant melanocytic tumors of the leptomeninges. Although the MR manifestations of this disease have been reported in a small series of cases, the usefulness of fluid-attenuated inversion recovery (FLAIR) MR findings has not been documented. We present a case of NCM that showed diffuse leptomeningeal hyperintensity on FLAIR images. This FLAIR finding may be a clue to the detection of leptomeningeal abnormalities in NCM.

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