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American Journal of Neuroradiology 25:1705-1708, November-December 2004
© 2004 American Society of Neuroradiology

Case Report
BRAIN

MR Spectroscopy in the Diagnosis of Cerebral Amyloid Angiopathy Presenting as a Brain Tumor

Yair Safriela, Gordon Szea, Kaye Westmarkc and Joachim Baehringb

a Department of Radiology, Neuroradiology Section, Yale University School of Medicine, New Haven, CT
b Departments of Neurology and Neurosurgery, Yale University School of Medicine, New Haven, CT
c Department of Radiology, Clear Lake Medical Center, Houston, TX

Address correspondence to Yair Safriel, MD, Department of Radiology, Neuroradiology Section, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520

Summary: We present two cases of focal, tumefactive, masslike lesions of diffuse cerebral amyloid angiopathy (CAA) that presented as areas of increased signal intensity on long TR sequences without contrast enhancement or restricted diffusion. MR spectroscopy revealed normal metabolite ratios and unremarkable spectra. Pathologic tissue showed CAA and CAA with angitis of the CNS. Tumefactive CAA is a rare condition, and we describe its characteristics at MR spectroscopy and diffusion-weighted imaging.




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Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X