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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 25:285-288, February 2004
© 2004 American Society of Neuroradiology

Case Report
BRAIN

A Rare Expression of Neural Crest Disorders: An Intrasphenoidal Development of the Anterior Pituitary Gland

Kathlyn Marsot-Dupuch^a, Wendy R. K. Smoker^b and Walter Grauer^c

^a Department of NeuroRadiology, Faculty Paris Sud, le Kremlin-Bicêtre, France
^b Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA
^c Department of Department of Radiology, Bethanien Spital, Zurich, Switzerland

Address reprint requests and correspondence to Dr. Kathlyn Marsot-Dupuch Bicêtre Hospital-Neuroradiology, 78 rue du Général Leclerc. Kremlin-Bicêtre, France 94 275

Summary: Congenital abnormalities of the pituitary gland are rare and may be associated with midline cranial, orbital, and facial anomalies and with hormonal insufficiency. Here we report a case of asymptomatic, abnormal migration of the adenohypophysis. The normally developed adenohypophysis was located in the sphenoid bone and developed on the intersphenoidal septum, extending from the superior pharyngeal wall to the floor of the sella turcica (craniopharyngeal canal). The abnormal migration of the pituitary gland was isolated without hormonal deficit, brain, or facial developmental anomalies.