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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 25:565-570, April 2004
© 2004 American Society of Neuroradiology

Case Report
BRAIN

A Case of Intravascular Lymphoma with Increased Regional Cerebral Blood Flow in I-123 IMP Single-Photon Emission CT

Chihoko Miyazaki^a, Masaya Mukai^b, Yuriko Kawaai^a, Miki Takeda^a, Norio Katoh^a, Syunsuke Nagano^a, Kozoh Kubo^a and Michifumi Kohno^b

^a Department of Medical Imaging, Sapporo City General Hospital, Sapporo, Japan
^b Department of Clinical Immunology and Hematology, Sapporo City General Hospital, Sapporo, Japan

Address reprint requests to Chihoko Miyazaki, MD, Department of Medical Imaging, Sapporo City General Hospital, N-11, W-13, Sapporo, 060-8604, Japan

Summary: This report documents a case of intravascular lymphoma (IVL) with increased regional cerebral blood flow (rCBF) disclosed at I-123 IMP single-photon emission CT (IMP-SPECT). A 73-year-old woman with IVL had high rCBF disclosed by IMP-SPECT before chemotherapy; rCBF was normal after one course of CHOP (cyclophophamide, vincristine, doxorubicin, and prednisone) chemotherapy. During her clinical course, she had an episode in which she showed increased rCBF in the left cerebral hemisphere at IMP-SPECT performed immediately after the recovery from the right hemiparesis.