American Journal of Neuroradiology 25:636-638, April 2004
© 2004 American Society of Neuroradiology
Case Report
HEAD AND NECK
Amyloidosis Concurrently Involving the Sinonasal Cavities and Larynx
a Department of Radiology, Tri-Service General, Hospital, Taipei, Taiwan
b Department of Otolaryngology—Head and Neck Surgery, Tri-Service General, Hospital, Taipei, Taiwan
c Department of Radiology, Mount Sinai School of Medicine, New York University, New York, New York
d Department of Otolaryngology, Mount Sinai School of Medicine, New York University, New York, New York
e Anatomy and Functional Morphology, Mount Sinai School of Medicine, New York University, New York, New York
Address correspondence to Peter M. Som, MD, Department of Radiology, Box 1234, Mount Sinai School of Medicine, One Gustave Levy Place, New York, New York 10029
Summary: Localized amyloidosis is an uncommon benign disorder. The purpose of this report is to present the case of a 21-year-old man who had localized amyloidosis simultaneously involving the sinonasal cavities and the larynx. The rarer sinonasal lesion demonstrated CT findings of adjacent "fluffy" bone changes, possibly representing a new finding suggestive of this disorder. At MR imaging, the amyloid had signal intensity similar to that of skeletal muscle on T1- and T2-weighted images. After contrast material administration, the amyloid enhanced at most minimally, but peripheral enhancement about the mass was present. The importance of this case lies in the multifocal presentation of this uncommon disorder, and the imaging findings herein may provide a new sign of this paranasal sinus disease.