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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 25:784-786, May 2004
© 2004 American Society of Neuroradiology

Case Report
BRAIN

Multiple Cerebral Aneurysms in Factor VII Deficiency

Andreas M. Schilling^a, Jens O. Heidenreich^a, Anja C. Oldenburg^a, Terttu Pietilä^b, Rüdiger Stendel^b and Karl-Jürgen Wolf^a

^a Department of Radiology and Nuclear Medicine, University Hospital Benjamin Franklin, Free University of Berlin, Germany
^b Department of Neurosurgery, University Hospital Benjamin Franklin, Free University of Berlin, Germany

Address correspondence to Jens O. Heidenreich, MD, Klinik und Poliklinik für Radiologie und Nuklearmedizin, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Hindenburgdamm 30, 12200 Berlin, Germany

Summary: A rare case of multiple cerebral aneurysms and factor VII deficiency is presented. The authors hypothesize a possible combined genetic defect similar to that of other conditions with clotting disorders. Different treatment options are discussed for factor VII deficiency in particular and multiple cerebral aneurysms in general. The authors advise treatment of all detected aneurysms in case of a subarachnoid hemorrhage rather than only treatment of the ruptured aneurysms in order to immediately start the so-called triple-H therapy.