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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 25:876-879, May 2004
© 2004 American Society of Neuroradiology

Case Report
HEAD AND NECK

Massive Calcium Pyrophosphate Dihydrate Crystal Deposition Disease: A Cause of Pain of the Temporomandibular Joint

Kathlyn Marsot-Dupuch^a, Wendy R. K. Smoker^b, Lindell R. Gentry^c and Karen A. Cooper^c

^a Department of Neuroradiology, Faculty of Paris-Sud, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France
^b Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA
^c Department of Radiology, University of Wisconsin Hospital and Clinics, Madison, WI

Address reprint requests to K. Marsot-Dupuch, Department of Neuroradiology, Faculty of Paris-Sud, Hôpital de Bicêtre, 78 rue du Général Leclerc. Le Kremlin-Bicêtre 94275. France

Summary: Calcium pyrophosphate dihydrate deposition (CPDD) disease is a disorder that occasionally affects the temporomandibular joint (TMJ) and temporal bone, causing pain (66.6% of cases), swelling (50%), trismus (36.8%), and hearing loss (22.2%). Diagnosis of CPDD is challenging because clinical symptoms and imaging features are not characteristic and may mimic a chondrosarcoma. When the diagnosis of CPDD of the TMJ is under consideration, conventional radiographs of the wrist or the knee may contribute to the final diagnosis. Imaging features of CPDD are discussed with a review of the literature.