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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 25:1037-1040, June-July 2004
© 2004 American Society of Neuroradiology

Case Report
PEDIATRICS

Appearance of an Interhemispheric Cyst Associated with Agenesis of the Corpus Callosum

Annemarie Stroustrup Smith^a and Deborah Levine^b

^a Harvard Medical School and the Harvard-MIT Division of Health Science and Technology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215
^b Departments of Radiology and Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215

Address correspondence to Deborah Levine, MD, Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215

Summary: We describe a fetus with agenesis of the corpus callosum (ACC) and Dandy-Walker malformation that developed a frontal paramidline cyst late in gestation. The interval appearance of the cyst occurred in concert with increasing size of the lateral ventricles, which supports the hypothesis that cysts associated with ACC can develop with increasing intraventricular pressure. Recognition of the potential for a changing appearance of neurologic abnormalities is important to providing appropriate patient counseling.