American Journal of Neuroradiology 25:964-968, June-July 2004
© 2004 American Society of Neuroradiology
Case Report
BRAIN
Acute Korsakoff Syndrome Following Mammillothalamic Tract Infarction
a Departments of Neurosurgery and Emergency Medicine, Yamagata Prefecture Central Hospital, Yamagata, Japan
b Department of Clinical Neurology and Neurosurgery, Center for Integrated Human Brain Science, Brain Research Institute, University of Niigata, Niigata, Japan
Address correspondence to Yuichiro Yoneoka, MD, PhD, Department of Functional Neurology and Neurosurgery, Center for Integrated Human Brain Science, Brain Research Institute, University of Niigata, 1757 Asahi-machi, Niigata, 951-8585, Japan
Summary: There are limited case reports of structural lesions causing Korsakoff syndrome. This report describes acute Korsakoff syndrome following localized, bilateral infarction of the mammillothalamic tracts (MTTs). Axial T2-weighted imaging revealed the lesions at the lateral wall level of the third ventricle and diffusion-weighted imaging confirmed that the left lesion was new and the right old. Korsakoff syndrome persisted 6 months after the onset. This case suggests that bilateral MTT dysfunction can lead to Korsakoff syndrome.
This article has been cited by other articles:
![]() |
E. V. Sullivan and A. Pfefferbaum Neuroimaging of the Wernicke-Korsakoff Syndrome Alcohol Alcohol., March 1, 2009; 44(2): 155 - 165. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. Kim, J. Ku, K. Namkoong, W. Lee, K. S. Lee, J.-Y. Park, S. Y. Lee, J.-J. Kim, S. I. Kim, and Y.-C. Jung Mammillothalamic functional connectivity and memory function in Wernicke's encephalopathy Brain, February 1, 2009; 132(2): 369 - 376. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Rahme, R. Moussa, A. Awada, I. Ibrahim, Y. Ali, J. Maarrawi, T. Rizk, G. Nohra, N. Okais, and E. Samaha Acute Korsakoff-Like Amnestic Syndrome Resulting from Left Thalamic Infarction Following a Right Hippocampal Hemorrhage AJNR Am. J. Neuroradiol., April 1, 2007; 28(4): 759 - 760. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. P. Duprez, B. A. Serieh, C. Raftopoulos, Y. Yoneoka, N. Takeda, A. Inoue, Y. Ibuchi, T. Kumagai, T. Sugai, K. Takeda, et al. Absence of Memory Dysfunction after Bilateral Mammillary Body and Mammillothalamic Tract Electrode Implantation: Preliminary Experience in Three Patients AJNR Am. J. Neuroradiol., January 1, 2005; 26(1): 195 - 198. [Full Text] [PDF] |
||||


